odontogenesis Flashcards

1
Q

define odontogenesis

A

formation of tooth tissues from stem cells originating in the ectoderm primary germ layer

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2
Q

when does odontogenesis begin

A

6th week

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3
Q

the ectoderm germ layer splits into what basic tissues

A

mesenchyme and epithelium (and then the development into specific tooth tissues)

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4
Q

2 stages of odontogenesis

A

epithelial and tooth germ

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5
Q

primary dental lamina stage

A

starts in the 6th week as 2 epithelial invaginations (first in the lower jaw and then in the upper jaw). these invaginations descend into the underlying mesenchymal tissue/ectomesenchyme and move posteriorly.

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6
Q

facial band in the primary dental lamina stage=

A

vestibular lamina

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7
Q

lingual band in the primary dental lamina stage=

A

primary dental lamina

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8
Q

vestibular lamina fate

A

cell death occurs in the center of the band to create the VESTIBULE space

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9
Q

primary lamina fate

A

it is ODONTOGENIC and become the odontogenic epithelial part of a tooth germ

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10
Q

epithelial bud stage

A

primary dental lamina cells will develop into an epithelial bud aka primary buds (surrounded by mesenchyme/ectomesenchyme). the epithelial bud is continuous with the primary dental lamina still.

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11
Q

time of primary bud appearance of the primary central incisors

A

6 wks in utero

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12
Q

time of primary bud appearance of the primary second molars

A

8 wks in utero

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13
Q

time of permanent bud appearance of the first molar

A

4 mo in utero

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14
Q

time of permanent bud appearance of the central incisor

A

5 mo in utero

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15
Q

time of permanent bud appearance of the second molar

A

10 mo postnatally

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16
Q

time of permanent bud appearance of the third molar

A

5 years postnatally

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17
Q

how many primary buds are in each arch

A

10

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18
Q

how many total buds arise from the primary dental lamina

A

16 in each arch (10 primary and 6 permanent molars)

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19
Q

where do succedaneous teeth arise from

A

their own secondary dental lamina that arises from the lingual side of the primary dental lamina

20
Q

how many succedaneous teeth are there

A

10 in each arch

21
Q

where do non-succedaneous teeth arise from

A

their own bud off the primary dental lamina

22
Q

epithelial cap stage

A

the epithelial buds form into epithelial caps

23
Q

what is in the ‘enamel knot’

A

concentration of epithelial cells in the center of the epithelial cap. acts as a signalling center to determine whether a tooth will develop to become an anterior or posterior tooth.

24
Q

epithelial bell stage

A

epithelial cap grows/develops into an enamel organ (bell-shaped epithelial structure).

25
Q

what are the 4 layers to an enamel organ

A
  1. inner epithelial layer
  2. stratum intermedium layer
  3. stellate reticulum epithelial layer
  4. outer epithelial layer
26
Q

what is the white material in the stellate reticulum layer of the enamel organ

A

glycoprotein

27
Q

what cells are derived from the inner epithelial layer

A

ameloblasts (form enamel)

28
Q

where does the secondary dental lamina arise from

A

the primary dental lamina…lingual to it. remember there is a secondary dental lamina for each succedaneous tooth so there are 10 in each arch

29
Q

4 stages of the epithelial stage of odontogenesis

A
  1. epithelial dental lamina stage
  2. epithelial bud stage
  3. epithelial cap stage
  4. epithelial bell stage (enamel organ)
30
Q

what is the tooth germ stage

A

development of the epithelium and the mesenchymal tissues. cells of these tissues become formative cells of dentin, enamel, cementum, and pulp tissues.

31
Q

what is a tooth germ

A

epithelial enamel organ and the closely associated ectomesenchymal tissue

32
Q

3 parts of the tooth germ

A
  1. enamel organ (epithelium)
  2. dental papilla (mesenchyme)
  3. dental follicle (mesenchyme)
33
Q

what is the fate of the enamel organ

A

inner epithelial cells–> ameloblasts

34
Q

is the enamel organ vascular or avascular

A

avascular

35
Q

what is the structure called that is the result of all the layers of the enamel organ coming/merging together after the formation of enamel

A

reduced enamel epithelium…a stratified epithelial layer

36
Q

what is the purpose of the reduced enamel epithelium

A

protect the enamel from surrounding connective tissue until the tooth enters the oral cavity

37
Q

what is the fate of the dental papilla

A

starts off as mesenchymal cells that become odontoblasts (create dentin), fibroblasts, and reserve cells. ultimately becomes the pulp tissue!

38
Q

is the dental papilla vascular or avascular

A

vascular

39
Q

what is the fate of the dental follicle

A

starts off as mesenchymal cells that become cementoblasts, fibroblasts, osteoblasts, and reserve cells (stem cells). ultimately becomes the periodontal ligament of the periodontium.

40
Q

is the dental follicle vascular or avascular

A

vascular

41
Q

through what structure is the enamel organ attached to the mesenchyme (papilla and follicle)

A

basal lamina

42
Q

the light acellular layer b/w the ameloblasts (in the inner epithelial layer) and the odontoblasts (in the dental papilla) is the future site of what

A

the dentinoenamel junction (DEJ)

43
Q

what is the cervical loop

A

a double epithelial layer at the base of the enamel organ where the outer and inner epithelial layers meet

44
Q

what is the double epithelial layer at the cervical loop called

A

hertwig’s epithelial root sheath

45
Q

what is the purpose of herwig’s epithelial root sheath

A
  1. determines root dentin outline

2. determines number of root canals a tooth has