Oral Microbiome and Biofilms (2) Flashcards
How many bacterial species are there?
770
What is the most predominant microbe in the oral microbiome?
bacteria
What is an example of a bacteria in the oral microbiome?
streptococcus salivarius
S. mutans
S. albicans
What percent of bacteria are unculturable?
30%
How many fungal species are found in the oral cavity?
9-23
What fungal spp dominates in the oral cavity?
Candida spp
What are other fungal spp in the oral cavity?
Cladosporium
Aspergillus
Saccharomyces
Fusarium
Aureobasidium
(found in 30% of healthy people)
What can Aspergillus cause?
mould
What group of viruses predominates in the oral cavity?
Herpes (90%)
Majority shed Herpes in saliva
When is Herpes virus found in saliva?
during acute/chronic phase
What is the second most predominant virus found in the oral cavity?
HPV (25%)
What disease is HPV associated with?
cancer (oncogenic)
What bodily fluid is HBV and HCV found?
blood, saliva, vaginal fluids and semen
Where may the priming of the oral microbiome begin?
in-uterine
oral microbiome of mother, microbial cells attach to oral epithelium
could reach blood supply and reach the placenta/ placental tissue
Does the oral microbiome begin after birth and does the birthing method effect this?
oral cavity is thought to be initially sterile
possibly caesarean/vaginal birth may effect this
Does breast feeding and formula effect the oral microbiome?
breastfed babies maintain a higher level of Streptococci at 12 months - may give some protection to other species taking over ecological niches
at 2 years this levels out (no difference)
What genera is in high abundance in the buccal mucosa?
streptococcus
Gamella
What genera is in high abundance in the hard palate?
streptococcus
Gamella
What genera is in high abundance in the keratinised gingiva?
Streptococcus
What genera is in high abundance in the saliva?
Streptococcus
Prevotella
What genera is in high abundance in the subgingival plaque?
Streptococcus
Prevotella
What genera is in high abundance in the throat?
streptococcus
Prevotella
What genera is in high abundance in the tongue dorsum?
Streptococcus
Prevotella
What sample type have a diverse genera?
subgingival plaque
