Introduction to fungal diseases (A)

Question 1

What kind of fungal infection would immunocompromised individuals be at risk of?

Answer 1

life threatening fungal infections

Question 2

What kind of fungus are healthy individuals at risk of?

Answer 2

superficially infecting fungi e.g. ringworm

Question 3

Where do the Candida albicans cause infection?

Answer 3

oral/oesophageal

systemic (bloodstream)

vaginal

Question 4

What is the mortality of candida albicans oral/oesophageal infection?

Answer 4

33-66%

Question 5

What do you call a patient with low levels of WBC?

Answer 5

Leukopenia

Question 6

What is mycology?

Answer 6

the study of fungi

Question 7

Define a fungus

Answer 7

A chemo-organotrophic eukaryote that lacks chlorophyll and forms spores. Its cell wall contains polysaccharides, often chitin or glucan, and it absorbs nutrients. Its membrane contains ergosterol as the major sterol. Classification is principally based on morphology.

Question 8

What composes the cell wall of fungi?

Answer 8

polysaccharides, often chitin or glucan

Question 9

What is the major ergosterol in the fungal cell membrane?

Answer 9

sterol

Question 10

What is the role of the ergosterol?

Answer 10

fungi and acts to maintain cell membrane integrity, similar to mammalian cholesterol

Question 11

What are the 3 classes of fungi?

Answer 11

mould
yeasts
mushrooms

Question 12

What is an example of a mould fungus?

Answer 12

aspergillus fumigatus

Question 13

What is mould?

Answer 13

filamentous form of fungi

Question 14

What is an example of a filamentous fungi?

Answer 14

penicillium fungi

Question 15

What is a hypha and its role in filamentous fungal growth?

Answer 15

one of the threads that make up the mycelium of a fungus, increase by apical growth, and are transversely septate or nonseptate

Question 16

Where does the fungal grow?

Answer 16

the hyphal apex

Question 17

What are the branches off the hypha of a filamentous fungi?

Answer 17

hyphal branch

Question 18

What separates hyphae from the next?

Answer 18

septa

Question 19

What structure of filamentous fungi is used to spread the fungi further?

Answer 19

conidiospore with chains of conidia, spread into the environment

specific to a muld

Question 20

What are the spores of ascomycetes called?

Answer 20

ascospores

Question 21

What fungus does not form spores?

Answer 21

candida

Question 22

What is the official name of bakers yeast?

Answer 22

Saccharomyces cerevisiae

spore forming within a sac

Question 23

What cells favour a unicellular habit?

Answer 23

yeast