Oral Conscious Sedation I Flashcards

1
Q

Sedative agents cross what barrier?

A

Blood-brain

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2
Q

Cause delayed gastric emptying.

A

Scleroderma and Amyloidosis

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3
Q

Fraction of the drug that reaches the systemic circulation.

A

Bioavailability

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4
Q

Can you titrate oral meds?

A

No- only IV

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5
Q

These molecules diffuse more readily.

A

Nonpolar, lipid-soluble molecules

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6
Q

Diffusion where molecules move from high to low concentration.

A

Passive diffusion

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7
Q

Ions pair up to form a neutral complex that can enter the cell by passive diffusion.

A

Ion pair transport

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8
Q

Engulfment by the cell membrane/internalization.

A

Pinocytosis

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9
Q

These bind to the drug.

A high degree of binding to these will keep the drug in the body longer, and the drug will have a greater effect.

A

Plasma proteins

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10
Q

Lipid soluble drugs stay in the body of ____ people longer.

A

Fat

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11
Q

Well-perfused organs.

A

Brain, heart, liver, kidneys

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12
Q

Metabolism involves making drugs polar or nonpolar?

A

polar, water-soluble so they can be excreted

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13
Q

Where most agents are metabolized.

A

Liver

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14
Q

Phase I reactions involve

A

Oxidation
Reduction
Hydrolysis

(Breaking down the drug).

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15
Q

Phase II reactions

A

Conjugation

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16
Q

When the drug is combined with glucuronic acid to make it more water soluble.

A

Conjugation

17
Q

Most drugs are eliminated thru this organ.

A

Kidney

18
Q

Stages of Anesthesia

A

I - Analgesia
II - Delirium/Excitement
III - Surgical Anesthesia
IV - Medullary Paralysis

19
Q

Type of sedation where

  • there’s a minimally depressed level of consciousness.
  • Cognition and coordination are modestly impaired.
  • Ventilatory and cardiovascular functions are UNimpaired.
A

Minimal sedation

20
Q

Sedation in which there’s a drug-induced depression of cosnciousness during which patients respond purposedully to verbal commands alone or accompanied by light tactile stimulation.

A

Moderate sedation

21
Q

Sedation that may require assistance in maintaining a patent airway and spontaneous ventilation may be inadequate.

Patients cannot be easily aroused.

A

Deep sedation

22
Q

Oxyhemoglobin absorbs light at what wavelength?

A

990 nm

23
Q

Deoxyhemoglobin absorbs light at what wavelength?

A

660 nm

24
Q

What do you want oxygen saturation to be in a person?

A

> 95%