Chronic Pain Control

Question 1

Nerve disorder where non-nociceptive stimuli elicit pain.

Pain is sharp, and rapid onset.

Often associated with “trigger points” around the affected nerve distribution.

Answer 1

Neuralgia

Question 2

Another name for trigeminal neuralgia.

Answer 2

Tic delareoux

Question 3

When systemic disease causes neural pain.

Answer 3

Neuropathy

Question 4

Using too much of this can mimic MS bc of lack of Vitamin B12

Answer 4

Nitrous

Question 5

Diabetics have this neural pain.

Answer 5

Neuropathy.

Question 6

Inflammation of a nerve.

Answer 6

Neuritis

Question 7

A pain disorder resulting from a NORMAL response to localized, irritative, non-neural disease.

Answer 7

Neuritis

Question 8

Types of neurotransmitters that cause pain.

Answer 8

1) Excitatory Amino Acids (EAA’s).

2) Tachykinins

Question 9

Examples of Tachykinins

Answer 9

Substance P

Neurokinin A and B

Question 10

Substance P is what kind of pain NT?

Answer 10

Tachykinin

Question 11

Types of EAA receptors

Answer 11

AMPA and NMDA

Question 12

EAA receptors that bind glutamate to mediate “First Pain.”

Answer 12

AMPA Receptors

Question 13

EAA receptors that bind aspartate to mediate “second pain.”

Answer 13

NMDA Receptors

Question 14

Rapid and transient pain

Answer 14

First Pain

Question 15

Delayed and prolonged pain.

Answer 15

Second Pain

Question 16

Types of Excitatory Amino Acids that cause pain.

Answer 16

Glutamate and Aspartate

Question 17

These inhibit the EAA receptors.

Answer 17

Opioids

Question 18

Inhibit Tachykinin receptors.

Answer 18

Tricyclic antidepressants.

Question 19

Inhibit Phospholipase A.

Answer 19

Corticosteroids

Question 20

Side effects of this is adrenal suppression.

Answer 20

Corticosteroids

Question 21

May cause hyperglycemia.

Answer 21

Corticosteroids

Question 22

Topical agent that depletes Substance P in the skin and mucosa.

Answer 22

Capsaicin

Question 23

Increases the effects of GABA to produce analgesia.

Answer 23

Baclofen

Question 24

Receptors where opioids bind.

Answer 24

Kappa

Question 25

Inhibit the reuptake of Serotonin

Answer 25

Tricyclic Antidepressants

Question 26

An alpha 1 antagonist that decreases pain.

Answer 26

Guanethidine.

Question 27

Alpha 2 agonsit

Answer 27

Clonidine

Question 28

An anti-convulsant used to treat trigeminal neuralgia and post-traumatic neuropathies.

Answer 28

Carbamazepine

Question 29

An anti-convulsant that’s a structural analogue of GABA, but doesn’t act at the GABA receptor.

Answer 29

Gabapentin