Oral Cancer & Premalignant Lesions

Question 1

Leukoplakia

apprance

differential 3

most cases are

Answer 1

• White patch that does not rub off
• Clinical term; differential includes
  
  • Hyperkeratosis
  • Dysplasia
  • Squamous cell carcinoma
• Majority (95%) of cases are hyperkeratosis

Question 2

Erythroplakia

Erythroleukoplakia (speckled)

apperance

diff 2

likely to represent

Answer 2

• Red patch does not rub off
• Clinical term; differential
  
  • Dysplasia
  • Squamous cell carcinoma
• Much more likely to represent dysplasia or SCC than leukoplakia (90%)

Question 3

Actinic Chelitis

occurs on

leads to

due to

prognosis

Answer 3

• Common premalignant change of lower lip vermillion
  
  • leads to atrophy of vermillion border
• Due to long term or excessive UV light
• Cancer develops in 6-10% of cases

Question 4

Squamous Cell Carcinoma

most common 2

Answer 4

• Most common intra-oral cancer
• Most common location- mid-lateral border of tongue

Question 5

Verrucous Carcinoma

what is it

app 4

Answer 5

• Low-grade form of SCC
  
  • low tendency to metastasize
• Slowly growing with white, rough, warty surface

Question 6

Basal Cell Carcinoma

what is it

app 2

characteristic

Answer 6

• Painless ulcer on sun exposed face (UV)
• Raised rolled border with central area of depression or ulceration
• Telangiectasia can be seen on borders
• Usually does not metastasize but locally destructive

Question 7

SCC VS BCC

3

Answer 7

• Basal cell carcinoma
  
  • above the lip-tragus line
  • Chronic sun exposure
  • Does NOT appear intra-orally
• SCC
  
  • Below lip-tragus line
  • Acute sun damage (sunburn)
  • Most common intra-oral cancer