Oral and Esophageal Pathology Pictures

Question 1

Answer 1

apthous ulcer or canker sore

Question 2

Answer 2

Irritation fibroma

Question 3

Answer 3

pyogenic granuloma

Question 4

Answer 4

geographic tongue

Question 5

Answer 5

Fordyce’s granules: heterotopic collections of sebaceous glands in the oral cavity.

Question 6

Answer 6

hairy leukoplakia

EBV in immunocompomise

Question 7

Answer 7

squamous papilloma of tonsil

Question 8

Answer 8

squamous papilloma

Question 9

Answer 9

leukoplakia

Question 10

Answer 10

erythroplakia

Question 11

Answer 11

actinic cheilitis

Question 12

Answer 12

actinic cheilitis

Question 13

Answer 13

squamous cell carcinoma of the tongue

Question 14

Answer 14

Sinonasal polyps. Above, low-power magnification showing edematous polypoid masses lined by epithelium. Right, high-power view showing edema and eosinophil-rich inflammatory infiltrate.

Question 15

Answer 15

Schneiderian papilloma, exophytic (septal) type. Above, the tumor has a papillary growth protruding from the surface respiratory epithelium composed of a thickened non-keratinized squamous (epidermoid) epithelium

Question 16

Answer 16

Schneiderian papilloma, inverted type. Endophytic or ‘inverted’ growth pattern consisting of thickened epithelial nests arising from the surface and growing down into the stroma; the surface epithelium has undergone squamous metaplasia and the stroma is composed of a myxomatous to fibrous tissue with admixed chronic inflammatory cells.

Question 17

Answer 17

, nasopharyngeal carcinoma, undifferentiated type. The syncytium-like nests of epithelium (arrow) are surrounded by lymphocytes. Right, in-situ hybridization for EBV (EBER) is positive in the neoplastic cells.

Question 18

Answer 18

Above right, oral cavity showing a white stone situated within the orifice of the parotid (Stensen’s) duct causing an obstructive sialadenitis (arrow).

Question 19

Answer 19

sialidenitis

salivary gland parenchymal changes include marked inflammation and acinar atrophy; ducts are dilated and filled with mucopurulent material (arrow).

Question 20

If this was taken from the parotid…

Answer 20

LESA

, the parotid gland parenchyma is replaced by a mature lymphocytic infiltrate in association with multiple germinal centers (arrows), as well as acinar atrophy and formation of lymphoepithelial lesions; this process is well demarcated from the adjacent salivary gland parenchyma, seen along the left side of this illustration.

Question 21

Answer 21

mucocele

Question 22

Answer 22

Pleomorphic adenomas may occur in major as well as minor salivary glands; above left, presentation as a firm, freely movable, painless parotid gland mass (arrow); above right, submucosal painless palatal swelling (arrow); MRI of parotid pleomorphic adenoma (lower right, arrow).

Question 23

Answer 23

pleomorphic adenoma

Question 24

Answer 24

warthin tumor

Question 25

Answer 25

Mucoepidermoid carcinoma growing in nests composed of squamous cells as well as clear vacuolated cells containing mucin (above right); Mucicarmine stains the mucin reddish pink (below left).

Question 26

Answer 26

Adenoid cystic carcinoma in a salivary gland. Above, low-power view. The tumor cells have created a cribriform pattern enclosing secretions. Right, perineural invasion by tumor cells.

Question 27

Answer 27

esophagitis

Question 28

Answer 28

endoscopic photo of the esophagus in a patient with primary eosinophilic esophagitis. The esophageal mucosa shows burrows, concentric rings, and is studded with whitish-gray nodular plaques and exudates. Above, medium-power view of primary eosinophilic esophagitis showing marked reactive squamous hyperplasia, numerous intraepithelial eosinophils (measuring >20 per high-power field), and accumulation of eosinophils in the superficial portions of the epithelium.

Question 29

Answer 29

Barret’s esophagus