opioid receptor targets Flashcards
1
Q
methadone
A
mu full agonist
kappa little or no effect
2
Q
buprenorphine
A
mu partial agonist
Kappa competitive antagonist
3
Q
butorphanol
A
mu partial agonist
full agonist at kappa
4
Q
Nalbuphine
A
mu antagonist
kappa full agonist
5
Q
Naloxone
A
competitive antagonist an MU Delta Kappa
6
Q
naltrexone
A
competitive antagonist an MU Delta Kappa
7
Q
methylnaltrexone relistor
A
competitive antagonist an MU Delta Kappa
8
Q
alvimopan entereg
A
GI specific mu receptor antagonist
9
Q
morphine
A
mu agonist
k small action
10
Q
Sufentinal
A
mu agonist
k and d small action
11
Q
The Gi pathway causes
5
A
analgesia euphoria sedation anti-diarrheal cough suppression
12
Q
B Arrestin pathway causes
6
A
dependence n/v resp depression constipation sedation euphoria
13
Q
Euxadoline-
A
mu agonist delta antagonist
from google "Eluxadoline is used to treat irritable bowel syndrome with diarrhea (IBS-D; a condition that causes stomach pain, cramping, or loose or watery stools) in adults. Eluxadoline is in a class of medications called mu-opioid receptor agonists. It works by decreasing bowel activity.
