Opiods Flashcards
1
Q
Hydromorphone
- MOA
- E 1/2t
- PharmK
- SE
- Contraindications
- Dose
a. IV Push
A
a. 0.5-2 mg q 4 hr
2
Q
Morphine
- MOA
- E 1/2t
- PharmK
- SE
- Contraindications
- Dose
a. Pain
b. Induction
c. Infusion
A
a. 2.5-15 mg IV q 6-8hr
b. 0.1 -1 mg/kg
c. 1 - 10 mg/hr
3
Q
Meperedine
- MOA
- E 1/2t
- PharmK
- SE
- Contraindications
- Dose
a. Pain
A
a. 50-100 mg IV
4
Q
Alfentanil
- MOA
- E 1/2t
- PharmK
- SE
- Contraindications
- Dose
a. Pain
b. Induction
c. Infusion
d. Additional Bolus
A
a. 10-20 mcg/kg
b. 25-100 mcg/kg
c. 0.25 - 0.75 mcg/kg/min
d. 5-10 mcg/kg
5
Q
Fentanyl
- MOA
- E 1/2t
- PharmK
- SE
- Contraindications
- Dose
a. Pain
b. Induction
c. Infusion
d. Additional Bolus
A
a. 1-3 mcg/kg
b. 4-20 mcg/kg
c. 0.01 - 0.05 mcg/kg/min
d. 25-100 mcg
6
Q
Remifentanil
- MOA
- E 1/2t
- PharmK
- SE
- Contraindications
- Dose
a. Pain
b. Induction
c. Infusion
d. Additional Bolus
A
a. 1-2 mcg/kg
b. 1-2 mcg/kg
c. 0.05 - 0.25 mcg/kg/min
d. 0.1-1 mcg/kg
7
Q
Sufentanil
- MOA
- E 1/2t
- PharmK
- SE
- Contraindications
- Dose
a. Pain
b. Induction
c. Infusion
d. Additional Bolus
A
a. 0.1 - 0.3 mcg/kg
b. 0.25-2 mcg/kg
c. 0.0015 - 0.01 mcg/kg/min
d. 2.5 - 10 mcg
8
Q
Nalbuphine
- MOA
- E 1/2t
- PharmK
- SE
- Contraindications
- Dose
a. IV Push
A
a. 0.1-0.3 mg/kg
9
Q
Butorphanol
- MOA
- E 1/2t
- PharmK
- SE
- Contraindications
- Dose
a. IV Push
A
a. 0.01-0.04 mg/kg
10
Q
Naloxone
- MOA
- E 1/2t
- PharmK
- SE
- Contraindications
- Dose
a. IM/ IV Push (Max)
A
a. 0.1-2mg over 30 sec q 2-3 mins (Max 10mg)
11
Q
Active Metabolites (Opioids)
A
- Morphine - Morphine-6-glucoronide (More pt than MSO4)
- Meperedine - Normepderedine (50%, 72hr E1/2, renal)
- Sufentanil - Desmethsufentanil (10%, watch in CRF)
12
Q
Opioids with Pulmonary 1st Pass Effect
A
- Meperidine - 65%
- Fentanyl - 75%
- Sufentanyl - 65%
