Benzos/Barbs

Question 1

Flumazenil (Romazicon)

1. MOA
2. E 1/2t
3. PharmK
4. SE
5. Contraindications
6. Dose
   a. Initial IV Push
   b. Repeat Dose (Max)
   c. IV Infusion

Answer 1

a. 0.2mg wait 2 mins
b. 0.1mg q 60secs (Max 3mg)
c. 0.1-0.4 mg/hr

Question 2

Diazepam (Valium)

1. MOA
2. E 1/2t
3. PharmK
4. SE
5. Contraindications
6. Dose
   a. IV Anticonvulsant
   b. IV Sedation Push
   c. IV Induction
   d. PO Sedation

Answer 2

a. 0.1 mg/kg
b. 0.2mg/kg
c. 0.5-1 mg/kg
d. 10-15 mg

Question 3

Midazolam (Versed)

1. MOA
2. E 1/2t
3. PharmK
4. SE
5. Contraindications
6. Dose
   a. IV Sedation Push (Max)
   b. IV Induction
   c. Pediatric PO Sedation

Answer 3

a. 1-2.5 mg (Max 5)
b. 0.1-0.2 mg/kg
c. 0.25-0.5 mg/kg (max 20)

Question 4

Lorazepam (Ativan)

1. MOA
2. E 1/2t
3. PharmK
4. SE
5. Contraindications
6. Dose
   a. IV Sedation
   b. PO Sedation (Max)

Answer 4

a. 1-2 mg

b. 50 mcg/kg (4mg)

Question 5

Thiopental (Sodium Pentothal)

1. MOA
2. E 1/2t
3. PharmK
4. SE
5. Contraindications
6. Dose
   a. IV Induction (Geriatric)
   b. IV Induction (Adult)
   c. IV Induction (Pediatric)
   d. IV Induction (Infant)

Answer 5

a. 2-3.5 mg/kg
b. 3-5 mg/kg
c. 6-7 mg/kg
d. 7-8 mg/kg

Question 6

Methohexital (Brevital)

1. MOA
2. E 1/2t
3. PharmK
4. SE
5. Contraindications
6. Dose
   a. IV Induction
   b. Peds PR

Answer 6

a. 1-2mg/kg

b. 20-30mg PR

Question 7

Active Metabolites (Benzos/Barbs)

Answer 7

1. Valium - Desmethyldiazepam (48-96hr E1/2t, equal potency)
2. Versed - 1-hydroxymidazolam (10%)
3. Thiopental - hydroxythipental (10-20%)