opiod pharmacolog

Question 1

how long is one course of circulation

Answer 1

1 min

Question 2

how do opiods work

Answer 2

Inhibit the release of pain transmitters at spinal cord and midbrain , modulate pain perception in higher centres

Alters the emotional perception of pain

Question 3

what is potency

Answer 3

whether a drug is ‘strong’ or ‘weak’ relates to how well the drug binds to the receptor,
the binding affinity

Question 4

opiod receptors?

Answer 4

MOP, KOP, DOP , NOP

Question 5

WHAT is tolerance

Answer 5

Down regulation of the receptors with prolonged use
Need higher doses to achieve the same effect

Question 6

what is dependance

Answer 6

psychological - craving, euphoria
Physical

Question 7

when does opiod withdrawal start

Answer 7

within 24 hrs
lasts about 24 hrs

Question 8

side effects of opiods

Answer 8

• Respiratory Depression
  Sedation
  Nausea and Vomiting
  Constipation
  Itching
  Immune Suppression
  Endocrine Effects

Question 9

what would you give for a morphine overdose

Answer 9

naloxone

Question 10

Main side effect of opiate use

Answer 10

Constipation

Question 11

Pain ladder

Answer 11

Mild pain
Moderate pain
Severe pain

Question 12

What to do for a patient in opiate induced resp depression

Answer 12

Call for help
ABC
naloxone-IV
Titration to effect

Question 13

Oral bioavailability for morphine

Answer 13

50%

Question 14

Examples of medications used for mild pain

Answer 14

Ibuprofen
Naproxen

Question 15

Medications you may give for moderate pain

Answer 15

Codeine
Tramadol

Question 16

Medication you would give for severe pain

Answer 16

Morphine