oogenesis Flashcards
when was the first 3 parent child born
2016
what is the purpose of a three parent child
help parents with lethal mitochondria DNA mutation
components of the oocyte
zona pellucida
vitelline membrane
cytoplasm
germinal vessicle
oogenesis definition
formation and development of oocyte
oogonium difinition
primordial cell that develops into oocyte(surrounded by single layer of cumulus cells)
oocyte definition
not fully developed ovum
ovum definition
the egg-cell capable of developing into a new individual
why do primary oocytes become dormant in meiosis I
prevent them from undergoing atresia to allow for max number of oocytes
T/F follicle develops from primordial to primary while arrested in meiosis I
TRUE
what resumes meiosis I
estrus-LH and FSH remove inhibitors
average number of oocytes ovulated in a lifetime for humans? Cows?
human: 500
cow: 350
what are projections on the ZP called? what to they do?
transdermal gap junctions to communicate between oocyte and cumulus cells
what protein makes up gap junctions
connexons composed of six sub units
what does the oocyte secrete that is necessary for follicular development
GDF-9(BMP-15)
T/F oocyte affects granulosa cell differentiation
TRUE(mural vs. cumulus)
