Oogenesis Flashcards

1
Q

Folliculogenesis

A

Formation and development of ovarian follicles = endocrine structures that participate in coordination of reproductive cycles and support development of oocyte

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2
Q

Oogenesis

A

Process of differentiation and release of a mature oocyte for fertilization

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3
Q

Mitotic Phase

A

PGCs colonize bipotential gonads - gonads differentiate into ovaries and PCGs differentiate into ooginia

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4
Q

Meiotic Phase

A

Characterized by onset of meiosis and formation of primary oocytes

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5
Q

Formation of Primordial follicles

A

1st layer of granulosa cells creates new biochemical environment within follicle which stimulates differentiation of oogonium

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6
Q

Primary Oocytes

A

Enter meiosis 1 which is then arrested at prophase 1 (diplotene stage)

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7
Q

Formation of Germinal Vesicle

A

Envelope surrounding large oocyte nucleus with arrested, dense DNA

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8
Q

Cytoplasmic Development

A

Characterized by substantial growth of cytoplasm and formation of specialized cellular structures

-activation of primordial follicles

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9
Q

Formation of Zona Pellucida

A

Synthes by oocyte, protects and covers ZP - important for fertilization

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10
Q

Formation of Gap Junctions

A

Cytoplasmic projections from granulosa cells cross ZP, critical for communication btwn granulosa and oocyte, granulosa cells take on many responsibilities for oocyte growth

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