Ondansetron

Question 1

Ondansetron
Indications
(1)

Answer 1

• significant nausea AND/OR vomiting

Question 2

Ondansetron
Contraindications
(5)

Answer 2

Absolute
- allergy/adverse drug reactions
- congenital long QT syndrome
- apomorphine therapy (parkinson’s disease)
- patients less than 2yrs
Relative
- first trimester pregnancy (only for extreme hyperemesis)

Question 3

Ondansetron
Presentation

Answer 3

• ampoule, 4mg/2mL
• orally disintegrating tablet, 4mg

Question 4

Ondansetron
Nausea/Vomiting
Adult Dose
IM

Answer 4

4-8mg
total max dose 8mg
must not be given within 8hrs of previous dose

Question 5

Ondansetron
Nausea/Vomiting
Adult Dose
PO

Answer 5

4-8mg
total max dose 8mg
must not be given within 8hrs of previous dose

Question 6

Ondansetron
Nausea/Vomiting
Adult Dose
IV

Answer 6

4-8mg (slow push 2-3mins)
total max dose 8mg
must not be given within 8hrs of previous dose

Question 7

Ondansetron
Nausea/Vomiting
Paediatric Dose
IV

Answer 7

100microg/kg (slow push 2-3mins)
total max dose 4mg
must not be given within 8hrs of previous dose

Question 8

Ondansetron
Nausea/Vomiting
Paediatric Dose
IM

Answer 8

100microg/kg (round to 5kg) (slow push 2-3mins)
total max dose 4mg
must not be given within 8hrs of previous dose

Question 9

Ondansetron
Nausea/Vomiting
Paediatric Dose >5yrs
PO

Answer 9

4mg
single dose only
must not be given within 8hrs of previous dose

Question 10

Ondansetron
Nausea/Vomiting
Paediatric Dose 2-4yrs
PO

Answer 10

2mg
single dose only
must not be given within 8hrs of previous dose