Ceftriaxone

Question 1

Ceftriaxone
Indications
(1)

Answer 1

suspected meningococcal septicaemia (with non-blanching petechial AND/OR pupruic rash)

Question 2

Ceftriaxone
Contraindications
(3)

Answer 2

Absolute
-allergy AND/OR adverse reaction to cephalosporin antibiotics
-known immediate OR sever hypersensitivity to penicillin OR carbapenem based drugs
Relative
-pts under 1mth (requires QAS consultation)

Question 3

Ceftriaxone
Presentation

Answer 3

vial (powder), 1g

Question 4

Ceftriaxone
Meningococcal Septicaemia
Adult Dose
IM

Answer 4

2g, 2 x 1g IM injections
single dose only

Question 5

Ceftriaxone
Meningococcal Septicaemia
Adult Dose
IV

Answer 5

2g
single dose only

Question 6

Ceftriaxone
Meningococcal Septicaemia
Paediatric Dose + 2 NOTES
IM

Answer 6

50mg/kg (rounded up to nearest 5kg)
single dose only
max dose 1g
NOTE - over 20kg give partial dose and adivse hospital
NOTE 2 - over 2mL must be given in 2 injections

Question 7

Ceftriaxone
Meningococcal Septicaemia
Paediatric Dose
IV

Answer 7

50mg/kg (rounded up to nearest 5kg)
single dose only
max dose 2g

Question 8

Ceftriaxone
Meningococcal Septicaemia
Adult Dose
IV - prep

Answer 8

reconstitute 2g of ceftriaxone with 18.8mL of water for injection in 20mL syringe, final concentration is 2g/20mL

Question 9

Ceftriaxone
Meningococcal Septicaemia
Adult Dose
IM - prep

Answer 9

reconstitute 2 x 1g of ceftriaxone with 2.4mL water for injection in two 3mL syringes, final concentration is 2 x 1g/3mL