Oncology (MR)

Question 1

Differentials for enlarged LN?

Answer 1

Infection Neoplasia Inflammatory Immune Mediated

Question 2

Ruleouts for Infection of LN?

Answer 2

Tooth Abscess Salivary Gland Erlichia Rocky Mtn Spotted Fever Lymes Fungal

Question 3

Pros and Cons of FNA (cytology)?

Answer 3

Cheap, Quick, Easy. Often gives dx Individual cells Cons: lack of tissue architecture Not always diagnostic sample Hemodilution and inflammation make it hard to decipher

Question 4

What Neoplasia enlarge 1 ln?

Answer 4

mast cell tumor of head/neck melanoma Lymphoma Metastatic cancer

Question 5

What is the most common oral tumor in dogs?

Answer 5

Melanoma

Question 6

With Cytology what is the 1st question to ask yourself? 2nd ?:

Answer 6

Is this a diagnostic sample Cell type What are cell types (3 main)? Round Epithelial Mesenchymal

Question 7

Mesenchymal cells nucleas?

Answer 7

Round or ovid

Question 8

Cytoplasm of Mesenchymal cells?

Answer 8

Spindle w/

Question 9

Diagnostics for Enlarged LN?

Answer 9

FNA Min Database

Question 10

Differentials for enlarged LN?

Answer 10

Infection Neoplasia Inflammatory Immune Mediated

Question 11

Ruleouts for Infection of LN?

Answer 11

Tooth Abscess Salivary Gland Erlichia Rocky Mtn Spotted Fever Lymes Fungal

Question 12

Pros and Cons of FNA (cytology)?

Answer 12

Pros: Cheap, Quick, Easy. Often gives dx Individual cells Cons: lack of tissue architecture Not always diagnostic sample Hemodilution and inflammation make it hard to decipher

Question 13

What Neoplasia enlarge 1 ln?

Answer 13

mast cell tumor of head/neck melanoma Lymphoma Metastatic cancer

Question 14

What is the most common oral tumor in dogs?

Answer 14

Melanoma

Question 15

With Cytology what is the 1st question to ask yourself? 2nd ?:

Answer 15

Is this a diagnostic sample Cell type What are cell types (3 main)? Round Epithelial Mesenchymal

Question 16

Mesenchymal cells: Nucleus? Cytoplasm? Exfoliation?

Answer 16

Nucleus: round to ovoid Cytoplasm: spindle or fusiform, often have wispy tails Cells exfoliate individually Occasional clumps Samples are often poorly cellular

Question 17

Mesenchymal Cancer type: _________________?

Answer 17

Sarcoma

Question 18

Epithelial Cells: Nucleus? Cytoplasm? Exfoliate?

Answer 18

Nucleus: round ? Cytoplasm: round, ovoid, or angular, distinct and intact cytoplasmic borders Exfoliate well, in sheets or clumps

Question 19

Epithelial Cells: Cancer type: _______________?

Answer 19

Carcinoma

Question 20

Difficulty with epithelial cell samples?

Answer 20

Bacteria cannot make dx until understand presence of bacteria

Question 21

Round cells: Nucleus Cytoplasm? Exfoliate?

Answer 21

Nucleus: round Cytoplasm: round, scant to moderate amount . Exfoliate well, and individually (discrete)

Question 22

Round cell Cancer types?

Answer 22

Lymphoma Transmissible venereal tumor Plasmacytoma Histiocytoma Mast cell tumor

Question 23

What is the Great Cytologic Pretender?

Answer 23

Melanoma Amelanotic melanoma - look like other cancers. Need histopath

Question 24

Criteria of malignancy?

Answer 24

High or variable: Anisokaryosis Anisocytosis Chromatin clumping Nuclear molding Multinucleation Abnormal mitotic figures or increased numbers of mitotic figures

Question 25

When do you want Histopathology?

Answer 25

-Tissue articture -background inflammation - cant get sample on cytology

Question 26

Histopath is very Dependent on?

Answer 26

sample quality and quantity

Question 27

2 Types of histopath for smapling? How do you choose?

Answer 27

Pretreatment biopsy Excisional biopsy How big is it? Will total removal be therapeutic?

Question 28

Your first chance to cut is your chance to?

Answer 28

Cure

Question 29

Why would you Ink for margins?

Answer 29

Tells pathologist where margins are so they know if tumor incision is complete = did you get it all?

Question 30

Immunohistochemistry: looks for cell markers. Great for dx of?

Answer 30

Melanoma

Question 31

When is a pre-treatment biopsy recommended?

Answer 31

Type of treatment altered; Extent of surgery altered Difficult area to reconstruct/ obtain complete margins Knowledge of tumor type & prognosis

Question 32

When is pretreatment biopsy not indicated?

Answer 32

Treatment or extent of surgery not changed (splenic mass, testicular mass) Surgical procedure for biopsy as risky as surgery (spinal cord tumor)

Question 33

What should you suspect in a dog that is acutely vomiting?

Answer 33

Aspiration