Oncology Flashcards
7 signs of Cancer remember pneumonic CAUTION (For O think of what Eric has a lot of on his back :D)
C-Change in bowel or bladder habit
A- A lesion that does not heal
U- Unusual bleeding or discharge
T- Thickening or lump in breast or elsewhere
I- Indigestion or difficulty swallowing
O- Obvious changes in warts or mole
N- Nagging cough or persistent hoarseness
Where else can cancer cells spread
Blood and lymph systems
What is remission
Disappearance of abnormal cells in bone marrow or blood
What type of diagnostic tests are taken for cancer
- Biopsy
- Bone marrow exam
- Chest x-ray
- CBC
- CT scan
- Cytology (like pap smear)
- Liver function studies
- MRI
- Evaluation of serum tumor markers (Carcinoembryonic and alpha-fetoprotein
- Guaiac test for occult blood
- Radiographic (Mammogram)
- Radioscope scanning ( Liver, brain, bone, lung)
- Tumor markers
What is important in cancer Pts in pain
ALWAYS assess client pain, how Pt describes the pain, do not under medicate cancer client who is in pain
What can you give the Pt if in pain medications
- Salicylates
- Acetaminophen
- NSAIDS (aspirin, ibuprofen) these three are given in mild - moderate pain
Severe pain
- Opioids (Codeine sulfate, morphine sulfate, methadone and hydromorphone (Dilaudid)
For neuropathic
- Anticonvulsants
- Antidepressants
- Opioids
Subcut inj and cont IV of opioids for rapid pain control
What is radiation ?
- Destroys cancer cells (minimal exposure to normal cells)
- Cells unable to divide because they are damaged
- Effective on tissues directly
What are side/adverse effects of radiation ?
- Alopecia
- Fatigue
What are the most common types of radiation used ? (2 types)
- External
- Brachytherapy
What is external beam radiation ?
- Radiation is external to the client
- Uses high - energy rays to kill cancer cells (may be used after breast cancer surgery to wipe out any cancer cells that remain)
Can radiation be used at the same time as Chemotherapy ?
Yes, for treatment of cancer that has spread to other body parts
Can external beam radiation be hazardous to others ?
No, The client does not emit radiation to others
What are side effects of external beam radiation ?
- Fatigue
- Swelling
- Itching
- Redness to peeling skin
- A sunburned like feeling in the treated area (of radiation)
Other therapy for radiation ?
Hormonal therapy with tamoxifen (anti- estrogen) for positive estrogen effect
Side effects of radiation to Abd
Nausea
Side effects of radiation to pelvis
Diarrhea
Is redness and sloughing of tissue expected in Pt on radiation ?
Yes
How long does radiation treatment therapy take ?
5-7 days
Care for radiation treated area ?
- Wash with plain water and pat dry
- DO NOT use soap over treated area (dries skin, may wash of markings for radiation)
- Avoid scrubbing or scratching
- NO lotions or powders
- AVOID sun exposure at least for a year after the completion of treatment
How long do you provide nursing care in a Pt receiving radiation ? what must you wear to determine amount of radiation, Distance between the Pt and nurse ?
- Provide nursing care for 30 min each shift
- Wear film badge to determine amount of radiation
- Distance between the Pt and nurse should be at least 4-8 ft
Brachytherapy ( Internal radiation )
- Direct contact, continuous contact with tumor for a specific time
Does the Pt emit radiation ( can it spread to others) ?
Yes, They can emit radiation for a specific amount of time
What is unsealed radiation ?
- Administer via oral or IV route by instillation into body cavities
Is unsealed radiation completely confined to one body area ?
No, It enters body fluids and eventually is eliminated
Explain removal of the seal radiation
- Client is no longer radioactive
- Inform to the client that cancer is no longer contagious
- Inform that sexual intercourse may be resumed after 7-10 days (If implant was cervical or vaginal)
- Provide douche if prescribed, if implant was placed in the cervix
- Administer ready to use saline enema as prescribed
- Client needs to notify MD if nausea, vomiting, diarrhea, frequent urination, vaginal or rectal bleeding, hematuria, foul smelling vaginal discharge, Abd pain or distention or a fever occurs
Explain brachytherapy in cervical cancer (internal radiation) Where is the implant placed and for how many days ?
- Radioactive implants such as pellets, rods, seeds, ribbons, wires, needles, capsules, balloons, or tubes are inserted
- Directly placed into the cervix for 1-3 days
What is HDR (high dose rate) brachytherapy ? How long is it applied for ?
A newer technique to avoid hospitalization, but not widely available
It is applied for 30 min- 1 Hr
What is LDR ( low dose rate) brachytherapy ?
This is usually used and requires hospitalization but it is not widely available
In what position should you be laying down when there is a radiation implant ? Can you have a pillow ? Are you allowed to go to the restroom ?
- Lying flat
- No pillow
- No restroom, it may dislodge
What should the nurse do when a radiation rod is displaced ? Think nursing safety
- Call radiation team
- Use gloves
- Use forceps
- Place rod in a lead container
What is bone marrow transplantation and peripheral blood stem cell transplantation most commonly used for ?
- Treatment for leukemia and lymphoma (cancer of lymph system)
What can BMT and PBSCT also be used to treat ?
- Neuroblastoma ( cancer of immature nerve cells from adrenal gland, ganglia, neck)
- Multiple myeloma (malignant plasma cells found in bone marrow)
What is the goal of treatment of BMT and PBSCT ?
- Get rid of all leukemic or malignant cells through high doses of chemotherapy
Where is transplantation administered through ?
- Central line
What does the Pt remain without during post transplantation period ? * Think of what high does of chemotherapy will cause the Pt. to lack of*
- The Pt remains without any natural immunity until donor stem cells begin to spread and grow
What are major concerns post transplantation ? think with a lack of natural immunity you are prone to get sick
- Neutropenia
- Severe thrombocytopenia
How to care for a patient with a radiation implant ?
- Lying supine (prevents dislodgement)
- No bearing down
- No bladder distension
What kind of diet are radiation implant Pt’s put on ?
Low fiber
Can a client undergoing radiation have sex ? Can it spread to the partner ?
Yes, Partner is not exposed with radiation
What is important if child bearing age when undergoing radiation ?
Where a condom
Can you have sex after chemotherapy ?
- Depends on WBC numbers
- Area being treated
Where is chemotherapy excreted and for how many hours ?
- Can be excreted through vaginal secretions
- Excreted for 48-72 hrs
Explain bone marrow aspiration procedure
- Pt under anesthesia
- Needle inserted in rear hipbone ( iliac crest ), this is where a large amount of bone marrow is located
- Extracted via needle and syringe
- Several skin and bone punctures to each hip is required in aspiration of bone marrow
Any surgical incisions or stitches after a bone marrow aspiration ?
None needed, only skin punctures where needle was inserted
At what age can person become a bone marrow donor ? What is important of the donor to be considered?
< 40
Must be the same ethnicity
Genetics should be the same
What is bone marrow harvest ?
Amount of bone marrow harvested depends on the size of the Pt and concentration of blood marrow cells in donor’s blood
How much bone marrow is usually harvested
1 or 2 quarts of marrow and blood are harvested this is only 2% of a person’s bone marrow, body will replace in 4 weeks
What may the Pt feel after anesthesia wears off ? (from BMT)
- Discomfort at harvest site
- Pain is similar to feeling of falling on hard ice can be controlled by Tylenol
Donors who are not also the BMT patient are usually discharged when ?
- After an overnight stay and can fully resume activities
What medication is not allowed to be taking in Pt receiving BMT
Motrin , due to risk of bleeding
What are 4 common types of leukemia * think ALL, CLL.
AML, CML*
- Acute lymphocytic leukemia
- Chronic Lymphocytic leukemia
- Acute Myeloid Leukemia
- Chronic Myeloid Leukemia
Which type of leukemia is common in children ? at what age usually ?
- Acute lymphocytic
- Age is < 15
what are signs and symptoms of leukemia which diagnostic blood tests are they low in ?
- Fever and chills
- Fatigue and weakness (ongoing)
- Frequent infections
- Losing weight without trying
- Swollen lymph nodes
- Enlarged liver or spleen
- Bleeds easily (ecchymosis and petechiae, bleeding under the skin), red tiny spots
- Overt bleeding ( Hematuria, nose bleeds, bleeding gums, increased menstrual flow, occult blood)
- Excessive sweating especially at night
- Bone pain and tenderness
Diagnostic Blood Tests:
- Low WBCs
- Low RBCs
- Low Platelets
- Decreased hemoglobin and hematocrit
What is the major cause in death in leukemia *Think what are you low in if you are prone to getting infections *
- Immunosuppression
List some things that important in protecting a leukemia Pt * think about what are things to prevent them from further getting sick and what to avoid*
- Protective isolations
- Frequent handwashing
- No visitors who are infectious
- Aseptic technique
- Keep all supplies separate from other Pts supplies
- No raw fruits and veggies ( on low bacteria diet)
- No fresh flowers or plants
- Do not leave water standing in room for more than 15 min
- Daily bathing using antimicrobial soap
- Avoid any invasive procedures ( injections, rectal thermometer, enemas, catheters)
- Change would dressings daily
- Monitor for cloudiness in urine
- Monitor skin and oral mucous membranes for signs of infection
What kind of medications would be prescribed in leukemia Pts ?
- Antibiotics
- Antiviral
- Antifungal
What are concerns about bleeding in leukemia Pts ? Think blood tests
- Risk for bleeding, if platelet count is less than 50,000 cells/mm
- If platelet count falls below 20,000 cell/mm Pt may need a platelet transfusion
- For anemia and fatigue packed red blood cells may need to be prescribed
Fatigue and nutrition for leukemia Pt. * What diet and how care for*
- Small frequent meals that are high in (Calories, protein, and carbohydrates), require little chewing to reduce using up energy
- Assist in self- care and mobility activities
- ## Rest periods
Multiple Myeloma
- Increased plasma cells and tumors within the bone
- These cells invade the bone marrow and soft tissues and develop into tumors that will destroy the bone (osteopenia to pathological fractures)