Endocrine Flashcards
Pancreas ( anatomy, where is its location ? )
- Pancreas is posterior to liver and behind the stomach
What is the pancreas function ?
Releases
- Pancreatic juices
- Enzymes
- Insulin ( secreted by cells of the islets of Langerhans
- Neutralizes stomach acid ( because it contains sodium bicarbonate)
What is a normal glucose level
70-110 mg/dL 60-110 mg/dL is acceptable
What are 3 major pancreatic enzymes ?
- Lipase
- Amylase
- Trypsin
What is the pancreas endocrine function ?
- Produces Insulin
- Produces glucagon
How does insulin work ?
- Glucose can enter freely into the cells
- Helps muscle and tissue oxidation of glucose (combine)
How does glucagon work ?
- Increases glyconeogenesis in liver
What is the exocrine function (digestive enzyme?)
- Fat digestion
What does lipase do ? What is the normal level ?
- Fat digestion
- 25-125 IU/dL or 60 - 160 somogyi units/dL
What does amylase do ? What is the normal level ?
- Carbohydrate digestion
- 22-51 U/L
What does trypsin do ? What is the normal level ?
- Protein digestion
Pancreatitis is it a priority medical condition ?
- Hyperglycemia with or without diabetes
- Priority medical condition, it is emergent
Cullen’s sign (Pancreatitis)
- Discoloration to around belly area Blue- black Greenish to brown or yellow - Abd pain - Indicates necrosis ( dead tissue)
Grey Turner’s Sign ( Pancreatitis )
- Blue discoloration of the flanks ( lumbar area)
- Bruising and ecchymosis ( retroperitoneal hemorrhage)
What are complications in pancreatitis ?
- Hypovolemia
- Hyperglycemia
- Tachycardia
- Hypocalcemia
- Shock
What is the diet for pancreatitis ?
- Limited fat
- Protein intake
- High calorie
- Bland
What are signs of having pancreatic tumors ?
- Jaundice ( initial or advanced )
- Anorexia/nausea/vomiting
- Indigestion
- Flatulence
- Weight loss
- Dark urine ( due to bile being reabsorbed)
- Clay colored stool
- Ascites and dull abd pain ( absent in early stage )
What is Whipple Surgery? what is It done for ?
- Whipple’s surgery is done for cancer of the
Head of the pancreas
Duodenum ( first section of the small intestine )
Jejunum ( Between duodenum and ileum )
Gallbladder and common bile duct
How long does it take for the resected liver to regenerate ?
6- 8 weeks
What treatment is given post op to Whipple’s Surgery or Pancreatitis ? what are these also used in ?
- Pancrease ( aids in digestion of food )
- Panncreatin ( pan 2400 ), used to treat malabsorption
- Pancrealipase (Creon)
- Viokase
Gallbladder
- Stores and concentrates bile to digest fats and oils