Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Step 2 CK > Oncology > Flashcards

Oncology Flashcards

1
Q

How is Breast CA usually found

A

ASx women on screening mamography

Palpation of mass by pt or doctor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Features of Breast CA mass

A

Palpable
Hard
Possible retraction of nipple
Painless

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Best initial test for breast CA

A

Bx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Best method to Bx breast CA

A

FNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the upside of doing core needle bx for breast CA

A

Can test for ER, PR, Her2/neu

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Most accurate dx test for breast CA

A

Open Bx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

When is mammography indicated

A

Screen for breast CA in gen pop starting at 50

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Why do mammography in pt who is already undergoing FNA for a mass

A

5-10% have b/l disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

When to do U/S in breast CA

A

Clinically indeterminant mass

  • Painful
  • Varies in size and pain during menses
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

When to do a PET in breast CA

A

Determine content of abnormal LNs not accessble to bx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is BRCA associated w/

A

Increased risk of breast CA in families

Ovarian CA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Does BRCA testing aid in mortality reduction

A

No

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Who gets sentinel node bx

A

All pts at time of lumpectomy or mastectomy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Why do sentinal node Bx

A

Neg eliminates need for axillary dissection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Who gets ER, PR testing

A

All pts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

When is hormone manipulation therapy done in breast CA

A

When ER or PR is positive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the role of localized radiation in breast CA

A

Prevent recurrence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What do all ER or PR positive pts receive

A

Tamoxifen, raloxifene or an aromatase inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Which hormonal manipulation drug is most likely to benefit a breast CA pt

A

Aromatase inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Tamoxifen AE

A

Endometrial CA

Clots

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Aromatase inhibitor AE

A

Osteoporosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

When is trastuzumab (herceptin) given

A

Her2/neu positive

Reduces risk of recurrent disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

When is adjuvant therapy given

A

Lesions >1cm

Positive axillary LNs

24
Q

When is tamoxifen given as PPx

A

Multiple 1st degree relatives have breast CA

25
Q

What lowers mortality from breast CA

A 
Mammography
ER/PR testing then tamoxifen/raloxifene
Aromatase inhibitors
Adjuvant chemo
Lumpectomy and radiation
Modified radical mastectomy
Trastuzumab
PPx w/ tamoxifen/raloxifene
26
Q

Presentation of prostate CA

A

Obstructive sx

Palpable lesion

27
Q

Best initial test and most accurate test for prostate CA

A

Bx

28
Q

MC complications of prostatectomy

A

ED

Urinary incontinence

29
Q

What is gleason grading

A

Measure of aggressiveness or malignant potential

30
Q

What does a high gleason grade suggest

A

Greater benefit of surgical removal

31
Q

What is NOT beneficial in prostate CA

A

Screening
Lumpectomy
Chemo
Hormonal manipulation

32
Q

Why is PSA controversial

A

No clear mortality benefit
Not routinely offered
NL does not exclude
>75 never done

33
Q

If pt is

A

Do it

34
Q

Elevated PSA and palpable mass, next step

A

Bx

35
Q

Elevated PSA and no palpable mass, next step

A

Transrectal U/S

36
Q

Elevated PSA,no palpable mass, Transrectal U/S shows mass, next step

A

Bx

37
Q

Elevated PSA,no palpable mass, Transrectal U/S doesn’t show mass, next step

A

Multiple blind bx

38
Q

When is surgery not possible in lung CA

A

B/L
Malignant pleural effusion
Heart, carina, aorta, vena cava involvement
Small cell

39
Q

Is there a screening test for ovarian CA

A

No

40
Q

Presentation of ovarian CA

A

Woman > 50

Increasing abdominal girth but still losing weight

41
Q

Best initial test for ovarian CA

A

U/S or CT

42
Q

Most accurate test for ovarian CA

A

Bx

43
Q

Rx ovarian CA

A

Remove large amounts of locally metastatic disease

Chemo

44
Q

What does testicular CA look like on PE

A

Painless lump

Doesn’t transilluminate

45
Q

Who is at increased risk of testicular CA

A

Hx of cryptorchidism

46
Q

Dx testing in testicular CA

A

Remove whole testical w/ inguinal orchiectomy

47
Q

What secretes alpha fetoprotein

A

Nonseminomatous CAs

48
Q

All testicular CAs have elevated

A

HCG

49
Q

How is staging done in testicular CA

A

CT abd, pelvis, chest

50
Q

Rx testicular CA

A

Orchiectomy
Radiation for local disease
Chemo for widespread disease

51
Q

Management of cervical CA

A

Hysterectomy

52
Q

Who gets HPV vax

A

All women 11-26

53
Q

Who gets PAP

A

Women at age 21 then every 3yrs until 65

54
Q

Low grade or high grade dysplasia on PAP, next step

A

Colposcopy for bx

55
Q

ASCUS on PAP, next step

A

HPV testing

56
Q

ASCUS on PAP, HPV+, next step

A

Colposcopy

57
Q

ASCUS on PAP, HPV-, next step

A

Repeat PAP in 6 months

Step 2 CK (21 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions