OB/Gyn Flashcards
MC first symptom of pregnancy
Amenorrhea
What leads to sx in pregnancy
Surge in estrogen, progesterone and b-HCG
First step in pt w/ sx of pregnancy
Pregnancy test
Cause of morning sickness
Increase in b-HCG by placenta
Define embryo
Fertilization to 8 weeks
Define fetus
8wks to birth
Define infant
Birth to 1 yr
Define developmental age
Days since fertilization
Define gestational age
Days/weeks since LMP (2 weeks longer than DA)
Nagele rule
LMP - 3mos + 7 days
First trimester
Fertilization till 12wks (DA) or 14wks (GA)
Second trimester
12/14 to 24/26
Third trimester
24/26 until delivery
Pre-viable fetus
Born before 24wks
Preterm
Born 25-37wks
Term
Born 38-42wks
Postterm
Born after 42wks
Gravidity
Number of times woman has been pregnant
Parity breakdown
Full term
Preterm
Abortion
Living children
First sign of pregnancy on physical exam
Goodell - softening of cervix
What is quickening
1st time mother feels baby kick
When is Goodell sign seen
4 weeks
Ladin sign
Softening of the midline of the uterus
6 weeks
Chadwick sign
Blue discoloration of vagina and cervix
6-8wks
When are telangiectasias/palmar erythema seen in pregnancy
First trimester
What is cloasma
Hyperpigmentation of face on forehead, nose and cheeks
Can worsen with the sun
When is cloasma seen in pregnancy
16 weeks
Linea nigra in pregnancy
Line of hyperpigmentation from xyphoid to pubic symphisis
2nd trimester
Best initial test when suspecting pregnancy
b-HCG
bHCG levels in pregnancy
Doubles every 48hrs for 4 wks
Peak at 10wks
Drops in 2nd trim
Increases to 20,000-30,000 in 3rd trim
How to confirm intrauterine pregnancy
U/S - gestational sac seen at 5wks
bHCG = 1000-1500
Cardio changes in pregnancy
Increased CO
Slightly lower BP
GI changes in pregnancy
Morning sickness
GE reflux as LES tone decreases
Constipation as large intestine motility decreases
Renal changes in pregnancy
Increased size of kidneys and ureters - risk of pyelo
Increased GFR
Decreased BUN/Cr
Heme changes in pregnancy
Anemia
Hypercoagulable state - Increased fibrinogen
Venous stasis
How often should mother be seen in 1st trim
Every 4-6 weeks
What is checked at 11-14 weeks
U/S confirming GA and check nuchal translucency
What does a thickened/enlarged nuchal translucency indicate
Down
When can fetal heart sounds be heard
End of 1st trim
Tests done during 1st trim
Blood tests
PAP
Gonorrhea/Chlamydia
Screening for chromosomal abnormalities
Most accurate method to determine GA at 11-14wks
U/S
What screen is done in 2nd trim
Triple or Quad - 15-20wks
What is the triple screen
MSAFP
b-HCG
Estriol
What is the quad screen
MSAFP
b-HCG
Estriol
Inhibin A
What does an increase in MSAFP indicate
Dating error
Neural tube defect
Abd wall defect
What increases the sensitivity of MSAFP
b-HCG
Estriol
Inhibin A
What other tests are done in 2nd trim
Auscultation of fetal HR
Quickening - 16-20wks
U/S for fetal malformation - 18-20wks
How often are 3rd trim visits
Every 2-3 wks
Every week after 36wks
When do Braxton-Hicks contractions occur
3rd trim
What are Braxton-Hicks contractions
Sporadic contractions that do not cause cervical dilation
Difference between Braxton-Hicks contractions and preterm labor
Preterm labor opens cervix
What should be done starting at 37 weeks
Cervix checked every visit
Testing at 27 weeks
CBC - replace Fe if Hb
Testing at 24-28 wks
Glucose load
Glc >140 @ 1hr, do glucose tolerance test
Testing at 36 weeks
Cervical culture for chlamydia and gonorrhea
- Rx if positive
Rectovaginal Cx for GBS
- ABX PPX in labor if positive
What is the glucose tolerance test
Ingest 100g glucose and check serum levels at 1, 2, 3hrs
Elevation in and 2 is gestational diabetes
What is given with Fe supplementation
Stool softeners
When is CVS done
10-13wks in advanced maternal age or known genetic disease in parent
What is the purpose of CVS
Fetal karyotype
Cathetier into intrauterine cavity to aspirate chorionic villi from placenta
When is amniocentesis done
11-14wks in advanced maternal age or known genetic disease in parent
What is the purpose of amniocentesis
Fetal karyotype
Needle transabdominally to remove amniotic fluid
When is fetal blood sampling done
Pts w/ Rh isoimmunization
How is fetal blood sampling done
Needle transabdominally into uterus to get blood from umbilical cord
MC site for ectopic pregnancy
Ampulla of fallopian tube
RFs for ectopic pregnancy
PID
IUD
Previous ectopic pregnancies
Presentation of ectopic pregnancy
Unilateral lower abd/pelvic pain
Vaginal bleeding
Hypotensive w/ peritoneal irritation if ruptured
Dx tests for ectopic pregnancy
b-HCG
U/S - Locate
Laparoscopy - Treat
Stabilize ruptured ectopic pregnancy
IV fluids
Blood products
DA
Baseline exams for medical rx of ectopic pregnancy
CBC
Blood type and screen
Tranaminases
b-HCG
Medical management of ectopic pregnancy
MTX for 4-7 days
If there is not a 15% drop in b-HCG, give 2nd dose
Still no decrease in b-HCG, surgery
When to avoid MTX
Immunocompromised Non-compliant Liver disease Ectopic > 3.5cm Fetal heartbeat present
Removal of ectopic pregnancy
Salpingostomy to preserve fallopian tube
Salpingectomy
Give to Rh- mothers during removal of ectopic
RhoGAM - Anti-D Rh IG
What is abortion
Pregnancy ends before 20wks or fetus
When do spontaneous abortions occur
Prior to 12wks
MCC spontaneous abortions
Chromosomal abnormalities
Maternal factors that increase risk of abortion
Anatomic abnormalities STDs APL Uncontrolled hyperthyroidism or DM Malnutrition Trauma Rh isoimmunization
Presentation of spontaneous abortion
Cramping abd pain
Vaginal bleeding
Stable or unstable
Dx tests for spontaneous abortion
CBC
Blood type and Rh
U/S
Only way to know type of abortion
U/S
Medical management of abortion
Misoprostol to induce labor
Complete abortion
No products found
F/U in office
Incomplete abortion
Some products found
D&C/medical
Inevitable abortion
Products intact
Intrauterine bleeding
Dilation of cervix
D&C/medical
Threatened abortion
Products intact
Intrauterine bleeding
No cervical dilation
Bed rest, pelvic rest
Missed abortion
Death of fetus but all products present
D&C/medical
Septic abortion
Infection of uterus
D&C w/ IV ABX (Levo, metro)
What increases the chances of multiple gestations
Fertility drugs
Presentation of multiple gestations
Exponential growth of uterus
Rapid wt gain by mother
Elevated b-HCG and MSAFP (First clue)
Dx test for multiple gestation
U/S to visualize
Complications of multiple gestations
Spontaneous abortion of 1 fetus
Premature labor and delivery
Placenta previa
Anemia
How is preterm labor diagnosed
Contractions w/ cervical dilation
RFs for preterm labor
PROM
Multiple gestations
Previous Hx
Placental abruption
Maternal RFs for preterm labor
Uterine anatomic abnormalities
Infection
Preeclampsia
Intraabdominal surgery
When does preterm labor occur
20-37wks
What must be evaluated in fetus during preterm labor
Wt
GA
Presenting part
When should delivery occur in preterm labor
Preeclampsia/eclampsia Maternal cardiac disease Dilation >4cm Maternal hemorrhage Fetal death Chorio 34-37 GA, >2500g
What should be given to stop preterm labor
Tocolytics
Betamethasone to mature lungs
MC used tocolytic
Mg sulfate
Side effects of Mg sulfate
Flushing
HA
Diplopia
Fatigue
What should be checked in pts getting Mg sulfate
Toxicity - resp depression, cardiac arrest
Check DTRs
Other tocolytics
CCBs - HA, flushing, dizziness
Terbutaline - palpitations, hypotension
Presentation of PROM
Gush of fluid from vagina
Dx test for PROM
Fluid in posterior fornix
Turns nitrazine paper blue
Ferning
When is PROM a big problem
Prolongued (labor starts more than 24hrs before delivery)
What can PROM lead to
Preterm labor
Cord prolapse
Placental abruption
Chorio - therefore do less exams w/ PROM
PROM w/ chorio, now what
Deliver
Term fetus, no chorio, PROM
Wait 6-12hrs for spontaneous delivery
Induce if there isn’t
Preterm fetus, no chorio, PROM
Betamethasone
Tocolytics
Amp + 1 dose azithromycin
Chorio PPX w/ PCN allergy
Rash - cefazolin + 1 dose azithro
Anaphylaxis - clinda + 1 dose azithro
Placenta previa
Abnormal implantation over internal cervical os
Increased risk of placenta previa with
Previous C-section
Previous uterine surgery
Multiple gestation
Previous placenta previa
Contraindication in 3rd trim bleeding
Digital vaginal exam
Next best step in 3rd trim bleeding
Transabdominal U/S
Presentation of placenta previa
Painless vaginal bleeding
Usually not till 28wks
Why is transvaginal U/S or digital vaginal exam not done in placenta previa
Can separate placenta from uterus
Complete placenta previa
Completely cover internal os (full moon)
Partial placenta previa
Partial covering of internal os (Half moon)
Marginal placenta previa
Placenta adjacent to internal os (crescent moon)
Vasa previa
Fetal vessel present over internal os
Low lying placenta
Implanted in lower segments of uterus but not covering internal os (
When is placenta previa treated
Large volume bleeding or drop in HCT
Rx placenta previa
Strict pelvic rest
No vaginal insertion
Indications for immediate C-section in placenta previa
Cervix >4cm
Severe hemorrhage
Fetal distress
How to prepare preterm fetuses for delivery
Betamethasone
Placenta accreta
Adheres to superficial uterine wall
Placenta increta
Adheres to myometrium
Placenta percreta
Invades uterine serosa, bladder wall or rectum wall
What happens if the placent doesn’t detach in delivery
Catastrophic hemorrhage and shock
Pt needs hysterectomy
Placental abruption
Premature separation of placenta from uterus
Complications of placental abruption
Life threatening bleeding Premature delivery Uterine tetany DIC Hypovolemic shock Sheehan
Precipitating factors for placental abruption
Maternal HTN Prior placental abruption Cocaine use External trauma Smoking
Presentation of placental abruption
Painful 3rd trim bleeding
Severe abd pain
Contractions
Fetal distress
Dx placental abruption
Transabdominal U/S, may not be seen
Concealed placental abruption
Blood is within uterine cavity
Placenta more likely to be completely detached
External placental abruption
Blood drains through cervix
Placenta more likely to be partially detached
Which placental abruption type has more complications
Concealed
Indications for C-section in placental abruption
Uncontrollable maternal hemorrhage
Rapidly expanding concealed hemorrhage
Fetal distress
Rapid placental separation
Indications for vaginal delivery in placental abruption
Separation limited
Fetal heart tracing assuring
Separation extensive and fetus is dead
When does uterine rupture occur
During delivery
RFs uterine rupture
Previous C-sections - Longitudinal > Low transverse Trauma - MVA Myomectomy Uterine overdistention - Polyhydramnios - Multiple gestation Placenta percreta
Presentation of uterine rupture
Sudden onset extreme abd pain
Abnormal bump in abd
No CTX
Regression of fetus
Rx uterine rupture
Immediate laparotomy w/ fetus delivery
Why is C-section not done in
Baby may not be in uterus but floating in abd
If uterus is repaired after rupture, how will future pregnancies be managed
Delivered via C-section at 36wks