Oncology Flashcards
Skin protection recommendations
Seek shade, especially between 10 AM and 4 PM
Wear a shirt; tightly woven fabrics are best
Use a broad-spectrum sunscreen, at least SPF 30, and reapply every 2 hours.
Wear a hat with at least a 2-3” brim.
Wear sunglasses to protect the skin around the eyes
ABCDE - Warning Signs of Melanoma
Asymmetry
Border
Color
Diameter
Evolving
Breast Cancer Screening Guideline for Average Risk Patients
Females
40-44yo = Annual mammogram is optional
45-54 = Yearly mammogram
>/=55 yo = Mammogram every 2 years or continue yearly
Cervical Cancer Screening Guideline for Average Risk Patients
Females
25-65 yo = Cervical cell analysis
Pap smear every 3 years
HPV DNA test every 5 years
Pap smear + HPV DNA test every 5 years
Colorectal Cancer Screening Guideline for Average Risk Patients
Males/Females >/= 45 yo
Stool-based tests:
Highly sensitive fecal immunochemical test (FIT) yearly
Highly sensitive guaiac-based fecal occult blood test (gFOBT) yearly
Multi-targeted stool DNA test (MT-sDNA) every 3 years
Visual exams of the colon and rectum:
Colonoscopy every 10 years (and as needed to confirm a positive result from any other test)
CT colonography (virtual colonoscopy) every 5 years
Flexible sigmoidoscopy (FSIG) every 5 years
Lung Cancer Screening Guidelines for Average Risk Patients
Male/Female >/= 50yo
Annual low-dose CT scan of chest if both of the following criteria are met:
Has at least a 20 pack-year smoking history
Still smoking or quit smoking within the past 15 years
Prostate Cancer Screening Guidelines for Average Risk Patients
Males (individualized decision for age)
If a patient chooses to be tested:
Prostate-specific antigen (PSA) blood test
+/- digital rectal exam (DRE)
Warning Signs of Cancer (CAUTION)
Change in bowel or bladder habits
A sore that does not heal
Unusual bleeding or discharge
Thickening or lump in the breast or elsewhere
Indigestion or difficulty swallowing
Obvious change in a wart or mole (ABCDE)
Nagging cough or hoarseness
Evaluation of Cancer
History and physical
Complete blood count
Comprehensive metabolic panel
Biopsy: removal of a tissue sample to identify cancer cells
Imaging tests: visualizes internal body structures
Biomarker tests: detects genes, proteins, or other substances released by cancer cells
Genetic tests: identifies specific cancer genes or mutations
Characteristics of a carcinoma
Forms from epithelial cells that line internal and external surfaces of the body.
Characteristics of leukemia
Originates in the bone marrow and usually affects leukocytes
Characteristics of lymphoma
Begins in the cells of the lymphatic system
Characteristics of multiple myeloma
Arises from plasma cells of the bone marrow
Characteristics of sarcoma
Develops in connective or supportive tissue (muscle, bone, cartilage)
Mostellar Equation
BSA (m^2) = sqrt(Ht (cm) x Wt (kg) / 3,600)
Calvert formula
Total carboplatin dose (mg) = (target AUC) x (GFR + 25)
Alkylating agents
Cyclophosphamide
Busulfan
Carmustine
Platinum-Based Compounds
Cisplatin
Carboplatin
Oxaliplatin
Anthracyclines
Doxorubicin
Mitoxantrone