Nonsterile Compounding Flashcards
Commercially available suspending agents
Ora-plus: Composed of a gel-like structure that keeps drug particles suspended and prevents settling. Slightly acidic to prevent drug degradation through oxidation. Bland taste - must be combined with Ora-Sweet for flavor.
Ora-Sweet: Similar to simple syrup. Provides flavor to Ora-Plus
Ora-Blend is a combo of Ora-Plus and Ora-Sweet
Binders
Acacia
Starch paste
Sucrose syrup
Compressible sugar
Diluents and fillers
Tablets/Capsules:
Lactulose
Mannitol
Sorbitol
Starches
Calcium salts
Cellulose powder
Liquids
Water
Glycerin
Alcohol
Topicals
Petrolatum
Mineral oil
Lanolin
Disintegrants
Alginic acid
Cellulose products
Starches
Flavorings and coloring agents
Non-caloric artificial sweeteners (Aspartame, saccharin, sucralose)
Glycerin
Dextrose
Sugar alcohols (mannitol, sorbitol, xylitol)
Stevia
D&C Red No. 3
Yellow No. 6
Caramel
Ferric oxide (red)
Lubricants
Magnesium stearate, calcium stearate, stearic acid
PEG
Glycerin
Mineral oil
Talc
Preservatives
Chlorhexidine
Povidone iodine
Sodium benzoate/benzoic acid, benzalkonium chloride, benzyl alcohol
Sorbic acid/potassium sorbate
Methyl/ethyl/propyl parabens
EDTA
Thimerosal
Cetylpyridinium chloride
Anti-foaming agents
Simethicone, dimethicone
Buffers
Hydrochloric acid
Acetic acid/sodium acetate
Citric acid/sodium citrate
Sodium hydroxide
Boric acid/sodium borate
Sodium bicarbonate/sodium bicarbonate
Sodium biphosphate/sodium phosphate
Potassium phosphate/metaphosphate
Adsorbents
Magnesium oxide/carbonate, kaolin
Coatings (regular)
Shellac, gelatin, gluten
Cellulose acetate phthalate
Gelling (thickening) agents
Agar, alginates, various gums [guar, xanthan, acacia (a natural gum)], gelatins, bentonite, cellulose, starches, cetyl alcohol, magnesium aluminum silicilate, poloxamer (pluronic) gels, polyvinyl alcohol, sorbitol
Humectants
Glycerin or glycerol, propylene glycol, PEG, lecithin, hyaluronic acid
