Oncology Flashcards
Speaking about splenic masses, which elements have been associated to a higher probability of a neoplastic process ?
Hemoabdomen
Thrombocytopenia
Larger body weight
Older age
Lower splenic mass to volume ratio
Lower mean splenic weight
Presence of thoracic metastasis
Anemia, abnormal RBC morphology
Explain mechanisms for multiple myeloma induced thrombocytopathia
M components can interfere with coagulation primarily by coating platelets, inhibiting platelet aggregation to damaged endothelial surfaces and release of platelet factor 3
What are the criteria for diagnosing multiple myeloma ?
> =2 of the following criteria:
BM plasmacytosis >20%
Bone lesions
serum monoclonal gammapathy
Bence Jones proteinuria
(>5% in cats, and visceral organ involvement)