Oncology Flashcards

1
Q

The recommended adjuvant therapy is chemo- RT for completely resected tumors in at least stage 2 cancer, except
a. Gastric cancer
b. Pancreatic cancer
c. Rectal cancer
d. Colon cancer

A

b. Pancreatic cancer

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2
Q

The following indicate poor prognosis in lung Ca, EXCEPT
a. Large cell histology
b. Female sex
c. Generalized weakness & fatigue
d. Weight loss> 10% in 6 months

A

b. Female sex

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3
Q

Most common malignancy associated with spinal cord compression
a. Colon cancer
b. Colon cancer
c. Breast cancer
d. Lymphoma

A

c. Breast cancer

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4
Q

Best biopsy procedure fir breast mass
a. Core needle
b. Excision biopsy
c. Incision biopsy
d. FNAB

A

a. Core needle

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4
Q

A decrease of tumor size by 20% from baseline is classified as:
a. Stable disease
b. Progressive disease
c. Complete response
d. Partial response

A

a. Stable disease

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5
Q

Most common site of bone metastasis or spinal cord compression:
a. Thoracic spine
b. Sacrum
c. Cervical spine
d. Lumbar spine

A

a. Thoracic spine

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6
Q

Most powerful prognostic factor for breast cancer
a. Histologic grade
b. ER/ PR status
c. Tumor size
d. lymph node metastasis

A

d. lymph node metastasis

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6
Q

TRUE about the management of non-small cell lung Ca (NSCLC), EXCEPT
a. Radiation is an alternative for medically unfit patients
b. Best supportive care is an option for advanced & metastatic disease
c. Sequential chemo-radiation increases
toxicity but has better local control compared to concurrent chemo-radiation
d. Surgical resection remains the treatment of choice if cure is the goal

A

c. Sequential chemo-radiation increases
toxicity but has better local control compared to concurrent chemo-radiation

|decreases

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6
Q

True about treatment of hepatocellular Ca (HCC), EXCEPT:
a. Systemic chemotherapy has limited survival benefit for patients with advanced disease
b. Patients who have ascites are poor surgical
candidates
c. Surgery offers the only potential cure for
early HCC
d. Liver transplantation may be considered
for locally advanced HCC with moderate cirrhosis

A

Surgery offers the only potential cure for
early HCC

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6
Q

Most common paraneoplastic syndrome
a. Hyperkalemia
b. Hypercalcemia
c. Hypouricemia
d. Hyperphosphatemia

A

b. Hypercalcemia

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6
Q

True of colorectal cancer, EXCEPT:
a. Left-sided tumors are annular in growth &
therefore seldom cause obstruction
b. Endoscopy with biopsy is the best method
of diagnosis
c. Proximal colon cancers are more common
d. Majority is adenocarcinoma

A

a. Left-sided tumors are annular in growth &
therefore seldom cause obstruction

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6
Q

In which type of cancer will you recommend
treatment with chemotherapy with or without RT in patients with good performance status because of the significant extension in survival?
a. Stage 3 unresectable liver cancer
b. Extensive stage small cell lung cancer
c. Stage 4 lung adenocarcinoma
d. Locally advanced pancreatic Ca

A

b. Extensive stage small cell lung cancer

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6
Q

Non-small cell lung cancer type with the worst
prognosis:
a. Large cell carcinoma
b. Adenocarcinoma
c. Bronchioalveolar carcinoma
d. Squamous cell carcinoma

A

a. Large cell carcinoma

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7
Q

Risk factors of Gastric cancer, EXCEPT:
a. Celiac disease
b. H. Pylori infection
c. Previous gastric resection
d. Gastric atrophy

A

Celiac disease

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7
Q

TRUE of small cell lung cancer (SCLC)
a. It may occur as solely extrapulmonary in 4% of cases
b. It is mostly peripheral in location
c. It is relatively chemo resistant but radiosensitive
d. It has less aggressive natural history than
non-small cell

A

a. It may occur as solely extrapulmonary in 4% of cases

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7
Q

A 60 y/o man comes to your clinic with complaint of recurrent epigastric pain over a year this time with associated weight loss. What is the single best diagnostic procedure to request to confirm your diagnosis?
a. Endoscopic ultrasound
b. Upper GI series
c. Upper GI endoscopy
d. Tri-phasic CT scan

A

c. Upper GI endoscopy

7
Q

True statements regarding treatment of small cell lung Ca (SCLC) EXCEPT:
a. Long-time survivors of SCLC are at high risk
for developing second primary malignancy
b. The cornerstone of therapy for extensive
disease; chemotherapy without thoracic irradiation
c. Concurrent chemo-radiation is the treatment of choice for limited disease
d. Prophylactic cranial irradiation is recommended for all patients with SCLC

A

d. Prophylactic cranial irradiation is recommended for all patients with SCLC

7
Q

Loss of regulatory influences
a. Autonomy
b. Anaplasia
c. Metastasis
d. Clonality

A

a. Autonomy

7
Q

Risk factors for esophageal cancer, EXCEPT:
a. Tylosis
b. GERD
c. Menetrier’s disease
d. Strictures from caustic injury

A

c. Menetrier’s disease

7
Q

A chemotherapeutic drug commonly associated with hemorrhagic cystitis
a. Dacarbazine
b. Cisplatin
c. lfosfamide
d. Temozolomide

A

c. lfosfamide

7
Q

Tumor lysis syndrome is most frequently associated with this malignancy
a. Liver cancer
b. Sarcoma
c. Lung cancer
d. Leukemia

A

d. Leukemia

7
Q

Recommended age for regular pap smear
a. 21 years old
b. 23 years old
c. 16 years old
d. 18 years old

A

a. 21 years old

8
Q

True of management of colon Ca, EXCEPT:
a. Surgery can be curative or palliative
b. Addition of radiation may improve local
control in incompletely resected colon Ca
c. Adjuvant chemo-radiation is standard
treatment for stage II and Ill colon Ca
d. Chemotherapy is the treatment of choice
for advanced and metastatic disease

A

c. Adjuvant chemo-radiation is standard
treatment for stage II and Ill colon Ca

rectal cancer

8
Q

Most common cause of cancer mortality
a. Colorectal cancer
b. Breast cancer
c. Lung cancer
d. Prostate cancer

A

c. Lung cancer

9
Q

A patient is diagnosed as colon cancer stage II high risk. He underwent hemicolectomy. What will be your next treatment?
a. Adjuvant chemotherapy alone
b. Adjuvant chemotherapy and radiation
c. No further treatment
d. Adjuvant radiation

A

a. Adjuvant chemotherapy alone