Oncology

Question 1

siADH cancer

Answer 1

small cell

Question 2

high ACTH causing cushings

Answer 2

small cell

Question 3

high PTH

Answer 3

squamous

Question 4

dehydration, lethargy, polydipsia and polyuria

Answer 4

hypercalcemia

Question 5

breast abscess or mastitis so hot swollen and tender breast but doesn’t respond to multiple courses of antibiotics

Answer 5

inflamm breast ca

Question 6

high calcium, renal insufficiency, anaemia and bone lesions (CRAB)

Answer 6

multiple myeloma

Question 7

hypercalcaemia of malignancy management

Answer 7

IV fluid rehydration then IV bisphosphonate infusion and calcitonin

Question 8

tumour lysis syndrome presentation

Answer 8

oliguria/AKI with arrhythmia and seizure (most common in lymphomas and germ cell tumours)

Question 9

tumour lysis syndrome management

Answer 9

calcium gluconate and insulin and dextrose for hyperkalaemia with fluids and consider dialysis
allopurinol to reduce uric acid

Question 10

tumour lysis syndrome marker

Answer 10

high urate (high potassium, high phosphate and low calcium)