Oncology Flashcards

1
Q

SE of bleomycin?

A

Lung fibrosis

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2
Q

SE of anthracyclines (doxorubin)?

A

Cardiomyopathy

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3
Q

SE of cisplatin?

A

Ototoxicity, peripheral neuropathy, hypomagnesia

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4
Q

Which variants of HPV are associated with cancer?

A

16 and 18

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5
Q

Features of SVC obstruction?

A
Dyspnoea
Swelling of face
Headache 
Visual disturbance
Pulseless jugular venous distension
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6
Q

CA 125 is associated with

A

Ovarian Cancer

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7
Q

CA 19-9 is associated with

A

Pancreatic Cancer

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8
Q

CA 15-3 is associated with

A

Breast Cancer

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9
Q

AFP is associated with

A

Hepatocellular carcinoma, teratoma

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10
Q

S-100 is associated with

A

Melanoma, Schwannomas

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11
Q

Bombesin is associated with

A

SCLC, Gastric Cancer, Neurblastoma

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12
Q

Management of neoplastic spinal cord compression?

A

high dose oral dexamethasone

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13
Q

BRACA2 is associated with

A

Breast cancer
Prostate cancer
Ovarian cancer

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14
Q

CEA is associated with

A

Colorectal cancer

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15
Q

Calcitonin is associated with

A

Medullary thyroid cancer

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16
Q

Which lung cancer has the strongest association with smoking?

A

Squamous cell

17
Q

SE of Cyclophosphamide

A

Haemorrhagic cysts

18
Q

Lung cancer most common in non-smokers?

A

Adenocarcinoma

19
Q

Most common tumour causing bone mets?

A

Prostate
Breast
Lung

20
Q

Most common bone mets sites?

A
SPINE
Pelvis
Ribs
Skull
Long bones
21
Q

Name an immune checkpoint inhibitor?

A

Nivolumab