Oncology Flashcards
most common source of metastatic parotid mass?
head and neck cutaneous squamous carcinoma
what kind of cells do carcinoid carcinoma arise from
enterochromaffin cells
what specifics of GIST tumors equate to highest risk of malignancy and mortality
size: > 5cm
mitoses: > 5 mitoses/hpf
best method to obtain tissue diagnosis for a pancreatic head mass
endoscopic ultrasound biopsy with needle stick
most common cause of parotid malignancy
metastatic disease
where are the deep inguinal lymph nodes located?
medial to femoral vein
what should you do if you see atypical ductal hyperplasia on a breast biopsy
excision biopsy
most common form of skin cancer?
basal cell carcinoma (80% of cases)
female patient with ER/PR + HER2 - breast cancer and high oncotype score. s/p resection with negative LNs…next step
chemotherapy given high oncotype AND hormone receptor positive
most common marker used to track epithelial ovarian cancer
CA-125 (Cancer Antigen 125)
role of CA-15-3
used in breast cancer surveillance after treatment
what constitutes locally advanced breast cancer
- large tumor > 5 cm
- involves chest wall/skin
- ulceration/satellite skin nodules
- inflammatory carcinoma
- lymph node involvement
what should all locally advanced breast cancer get
neoadjuvant chemotherapy
Adjuvant radiation
risk of ovarian cancer in BRCA 1
40-60%
risk of ovarian cancer in BRCA2
15-30%
What should you get on patient prior to starting Trastuzumab
echocardiogram
- most serious SE if cardiomyopathy
Nivolumab
mab to programmed death-1 and its ligand
Ipilimumab
mab to CTLA-4
Rituximab
mab to CD20
most common chemotherapeutic agents for pseudomyoxoma peritonei
- cisplatin
- doxorubicin
- mitomycin-c
leading cause of superior vena cava syndrome
lung carcinoma (Pancoast tumor)
patient had abdominal radiation and two years later has refractory diarrhea, biopsy from colonoscopy shows patchy thickening of the basement membrane with lymphocytic infiltration of the lamina propria
microscopic colitis
treatment for microscopic colitis
steroids (budesonide)
surgery recommended to patient with inflammatory breast cancer who responded to neoadjuvant therapy
mastectomy with axillary lymph node dissection (modified radical mastectomy)