Infectious Disease

Question 1

When are beta-lactam antibiotics most effective, regarding pharmacokenetics

Answer 1

when drug levels exceed minimum inhibitory concentration for greater than 50% of the time

Question 2

what class of drug is ertapenem

Answer 2

beta-lactam antibiotic

Question 3

mechanism of action of ciprofloxacin

Answer 3

inhibition of bacterial DNA gyrase

Question 4

inhibition of bacterial DNA gyrase, give antibiotic

Answer 4

ciprofloxacin

Question 5

inhibition of dihydropteorate synthetase, give antibiotic

Answer 5

Bactrim

Question 6

Bactrim mechanism of action

Answer 6

inhibition of dihydropteorate synthetase, give antibiotic

Question 7

inhibition of protein synthesis by binding to 30S ribosomal subunit, give class of drug

Answer 7

aminoglycosides

Question 8

inhibition of protein synthesis by binding to 50S ribosomal subunit, give drug class

Answer 8

macrolides

Question 9

Which strains of HPV are associated with condylomata acuminata?

Answer 9

HPV 6 and 11

Question 10

SSI rate in class I wound

Answer 10

1-5%

Question 11

SSI rate in class II wound

Answer 11

3-11%

Question 12

SSI rate in class III wound

Answer 12

10-17%

Question 13

SSI rate in class IV wound

Answer 13

> 27%

Question 14

what part of LPS gives its toxic properties

Answer 14

Lipid A region

Question 15

Patient getting antibiotics experiencing ototoxicity and nephrotoxicity, what class of antibiotics are they getting?

Answer 15

Aminoglycosides

Question 16

Common aminoglycoside you might see on the wards

Answer 16

gentamicin