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Medicine Finals > Oncology > Flashcards

Oncology Flashcards

1
Q

Which cancer is associated with CA125?

A

Ovarian cancer

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2
Q

Which cancer is associated with CA19-9?

A

Pancreatic cancer

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3
Q

Which cancer is associated with CA15-3?

A

Breast cancer

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4
Q

Which cancer is associated with S-100?

A

Melanoma

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5
Q

Which cancer is associated with calcitonin?

A

Medullary thyroid cancer

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6
Q

Which cancers which most commonly cause bone metastases?

A

Prostate
Breast
Lung

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7
Q

What are features of bone metastases?

A

Bone pain
Pathological fractues
Hypercalcaemia
Raised ALP

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8
Q

What side effect does vincristine cause?

A

Peripheral neuropathy

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9
Q

Which side effect does bleomycin cause?

A

Pulmonary fibrosis

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10
Q

Which side effect does cyclophosphamide cause?

A

Nephrotoxic/Bladder toxic

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11
Q

Which side effect does methotrexate cause?

A

Nephrotoxic, myelosuppression

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12
Q

Which side effect does asparagine cause?

A

Neurotoxicity

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13
Q

Which side effect does doxorucbicin cause?

A

Cardiotoxicity

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14
Q

Which side effect does cisplatin cause?

A

Nephrotoxic/ototoxicity

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15
Q

What is superior vena cava obstruction and how is it managed?

A

Complication of lung cancer
Dyspnoea
Swelling of the face, neck and arms
Headache + visual disturbance

Ask patient to lift arms above head - facial congestion, cyanosis and respiratory distresss

Management - sit them up, tenting

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16
Q

How does metastatic spinal cord compression present and how is it managed?

A

Back pain - worse on lying down/coughing/sneezing
Lower limb weakness
Sensory loss or numbness

Urgent MRI Spine
Oral Dexamethasone
Spinal decompression surgery

17
Q

What are early side effects of radiotherapy?

A 
Tiredness
Fatigue
Skin erythema
Alopecia
Mucositis --> Diarrhoea, dysuria
18
Q

What are late side effects of radiotherapy?

A 
Skin pigmentation changes
pulmonary fibrosis
infertility
secondary cancer
constrictive pericarditis

Medicine Finals (32 decks)

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