Dermatology Flashcards
How does rosacea present?
Flushing of the forehead, nose and cheeks
Telangiectasia
May be papules and pustules
Can progress to rhinophyma
What is mild rosacea?
Erythema or telangiectasia only
How is mild rosacea managed?
Lifestyle changes eg avoid sun, wear sunscreen, avoid exercise, avoid alcohol
If erythema only and no telangiectasia - topical Brimonidine gel
What is moderate rosacea?
Limited papules and pastules
How is moderate rosacea managed?
Topical metronidazole
Also topical azelaic acid
What is severe rosacea?
Extensive papules and pustules
How is severe rosacea managed?
Oral antibiotics e.g. oxytetracycline
How can telangiectasia be managed in rosacea?
Laser therapy
What is the stepwise approach to managing acne?
1) topical treatment e.g. benzoyl peroxide/retinoid/salicylic acid/azelaic acid
2) combination topical treatment
3) topical antibiotic - usually a tetracycline/erythromycin
4) oral antibiotics - usually a tetracycline (e.g. doxycycline) unless pregnant/breastfeeding/under 12
5) oral COCP in women
6) oral isotretinoin
What needs to be co-prescribed with an oral antibiotic in acne?
A topical benzoyl peroxide/retinoid to reduce chance of antibiotic resistance
Which antibiotic is most commonly used in acne?
A tetracycline e.g. doxycycline, oxytetracycline
Where does eczema most commonly affect?
In infants - cheeks
In older children and adults - flexures SYMMETRICAL!!
What is the first line management for eczema?
Emollients
Mild eczema/eczema on face - mild topical steroid
Moderate to severe eczema - moderately potent or potent topical steroid
What is an example of a mild topical steroid?
0.1% Hydrocortisone
What are examples of moderate potency topical corticosteroids?
Betamethasone 0.025% or Clobetsone 0.05%
What are examples of potent topical steroids?
Fluticasone 0.05%
Betamethasone 0.1%
What is an example of a very potent topical steroid?
Clobetasol 0.05%
What type of hypersensitivity reaction is allergic contact dermatitis?
Type IV
How does psoriasis present?
Well defined red scaly patches on the skin
Elevated plaques
Overlaying white/silver scale
Symmetrical distribution
What are nail changes seen in psoriasis?
Pitting
Oncholysis (lifting)
What is the stepwise management of psoriasis in primary care?
1) topical potent corticosteroid + vitamin D analogue (both once daily)
2) vitamin D analogue twice a day
3) topical potent corticosteroid twice a day or coal tar preparation twice a day
How can psoriasis be managed in secondary care?
Ultraviolet B phototherapy
Immunosuppressants
What is the first line immunosuppressant in psoriasis?
Methotrexate
How is scalp psoriasis managed?
Potent topical corticosteroid once daily for 4 weeks
How is psoriasis on the face/flexures/genitals managed?
Mild to moderate potency corticosteroid
What are non dermatological causes of pruritus?
Liver disease Iron deficiency anaemia Chronic kidney disease Polycythaemia Lymphoma
What is dermatitis hepatiformis?
Itchy vesicular lesions on extensor surfaces - knees, elbows, buttocks
Associated w/ coeliac
Which dermatological condition is associated with coeliac disease?
Dermatitis herpetiformis
What is the treatment for dermatitis herpetiformis?
Gluten free diet
Dapsone
Which medications exacerbate psoriasis?
Beta blockers
Lithium
Antimalarials
NSAIDs
ACE inhibitors
Alcohol
What is eczema herpeticum and how does it present?
Viral infection that usually presents in children with atopic eczema
Rapidly worsening, painful eczema with clustered blisters.
May be assocated fever and systemic illness
Which virus causes eczema herpeticum?
HSV1/HSV2
How is eczema herpeticum treated?
Aciclovir - oral or IV
What is erythema multiforme?
A hypersensitivity reaction usually triggered by infection (usually HSV or Mycoplasma)
Which infections most commonly trigger erythema multiforme?
HSV
Mycoplasma pneumoniae
How does erythema multiforme present?
Target lesions
Sharply demarcated lesions
Initially on back of hands and feet, then also on torso
Hypersensitivity reaction most commonly caused by HSV
How is erythema multiforme treated?
No treatment needed - self limiting
What is erythema nodosum?
An inflammatory disorder of the subcutaneous fat
How does erythema nodosum present?
Bilateral tender erythematous modular lesions usually on the shins
What are causes of erythema nodosum?
Associated with IBD, TB, sarcoidosis, pregnancy
How is erythema nodosum treated?
Self-limiting
Can give NSAIDs
What is erythroderma?
More than 95% of the skin is involved in a rash
What are complications of erythroderma?
Hypothermia
Dehydration (fluid loss)
How does pityriasis rosea present?
- Starts with a ‘Herald patch’ on trunk
2. Then scaly patches all over body
How is pityriasis rosea treated?
Self limiting - resolves in 6 weeks
Which rash starts with a herald patch and then goes on to a fir tree rash?
Pityriasis rosea
What is guttate psoriasis?
A rash precipitated by a streptococcal infection (usually 2-4 weeks before)
How does guttate psoriasis present?
Scaly tear drop papules on the trunk
How is guttate psoriasis managed?
Usually resolves spontaneously within 2-3 months
Can use topical psoriasis agents
What is pityriasis versicolour?
Cutaneous fungal infection
Which fungus causes pityriasis versicolour?
Melassezia furfur
How does pityriasis versicolour present?
Hypopigmentation patches on the skin
Scaly
May be itchy