Oncology Flashcards
Apocrine gland carcinoma px
1-2yrs if mass and LN excisions (and no adjunct treatment)
Highly malignant and metastatic potential
Perianal adenoma px
Good - commonly benign
Surgical margins required for a MCT
> 3cms + deep fascial plane
+ chemo/radiation
Soft tissue sarcoma behaviour
locally invasive - slow to met but will
may need radical excision ie. amputation
melanoma tx options
sx excision + vaccine + chemo
FNA limitations
- fibrous/sarcomas do not exfoliate well
- cannot rule anything out - can only rule in
- cannot grade neoplasia
A mass you suspect is malignant would you rather a excision or incisional biopsy?
- incisional (but do not extend margins!!)
- excisional makes potential re-resection difficult
what dog breed is associated with apocrine gland carcinomas?
cocker spaniels
why is minimal manipulation of the tumour important?
to prevent exfoliate of tumour cells + to not stimulate release of cytokines (MCT - histamine)
give an example of a biologic margin
fascia, tendon, cartilage
– collagen rich, low vascularity = natural barrier
what is a marginal excision?
en bloc removal of a tumour and pseudocapsule ‘shell out’ – for benign tumours (lipomas)
what is considered a wide margin?
> 3cm
what is considered a narrow margin?
<2-3cm
what tumour types require wide excision?
- plasmacytoma
- mast cell tumour (G1-2)
- cutaneous melanoma
’ well contained malignant disease’
which tumour types require radical excision?
infiltrative, highly malignant disease
always submit excised tissue for histologic examination –> surgical site marking
Why?
to confirm the diagnosis and confirm complete excision (good margins)
what are your options when you receive histo report that you have ‘dirty margins’?
- Revisit surgical options: en bloc excision/radical excision of previous site
- Adjunctive therapy - radiation/chemo
a digital melanoma is more likely to be malignant or benign?
malignant