Omics and Epigenetics Flashcards
What are the aims and objectives of the study on omics and epigenetic technologies in ecotoxicological studies?
To introduce the applications and challenges of omics and epigenetic technologies in ecotoxicological studies.
What is ‘Omics’? in context of biological sciences
Areas attempting to elucidate complex interactions between molecules in the different systems biology layers.
What are the 4 main types of omics?
Genomics
Transcriptomics
Proteomics
Metabolomics
What do DNA microarrays help in the context of ecotoxicology?
DNA microarrays help to develop predictive simulation models of toxic effects and are ideal to screen many genes in one step
What is Next Generation Sequencing (NGS) and its significance?
tool for rapid and cost-effective sequencing, used to reveal the presence and quantity of RNA in a sample at a given moment, analyzing the cellular transcriptome
Define ‘Gene of Interest’ (GoI)
refers to sequences of interest in a study,
often used in the context of analyzing specific genes involved in biological processes.
What are the 2 categories in Proteomics?
Expression proteomics
Functional Proteomics
What are ‘Expression Proteomics’?
What proteins are expressed in the sample at a given time.
What are ‘Functional Proteomics’?
to understand how proteins perform and interact with each other and other biomolecules
Define Epigenetics
refers to changes in the expression of genomic information at the level of transcription, translation or post-translation
what is Epigenetics relevance in Ecotoxicological studies
How genes are activated or silenced in response to environmental chemicals
What is DNA Methylation? and its relevance in Ecotox
the addition of a methyl group (-CH₃) to the DNA molecule, typically at the 5th carbon
it’s a response and biomarker for Environmental exposure
