OME - Dementia Flashcards

1
Q

DDx memory loss?

A
  1. Dementia
  2. Amnesia
  3. Delirium
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2
Q

Presentation dementia?

A
  1. Cognitive impairment - loss ADLs / executive function
  2. Memory Loss
  3. Slow onset: chronic course
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3
Q

Presentation amnesia?

A
  1. No cognitive impairment

2. Only Memory loss

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4
Q

Presentation delirium?

A
  1. Cognitive impairment
  2. Memory Loss
  3. Rapid onset: waxes and wanes
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5
Q

Score on MMSE indicative of dementia / cognitive impairment?

A

Less than 22

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6
Q

What is mild cognitive impairment?

A
  1. MMSE positive for impairment

2. ADLs / executive function not impacted

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7
Q

Reversible imitators of dementia? Test to rule out?

A
  1. Hypothyroidism: TSH / T4
  2. BMP: Cr/BUN
  3. Cirrhosis: LFTs:
  4. B12
  5. Depression
  6. Syphilis
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8
Q

Preferred imaging in Dementia?

A

CT

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9
Q

Most common for dementia?

A

Alzheimer’s disease

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10
Q

Pathology Alzheimer’s?

A

Plaques and tangles

Associated with chromosome 21

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11
Q

Presentation Alzheimer’s?

A
  1. ST memory goes first, then LT
  2. Elderly, slow onset
  3. Usually spares social graces
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12
Q

CT alzheimers?

A

Diffuse cortical atrophy

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13
Q

Rx Alzheimer’s?

A
  1. Supportive care

2. Family education

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14
Q

Presentation Frontotemporal degeneration?

A

“Pick’s Disease”

  1. Personality Goes first: NO FILTER
  2. Memory retained at first
  3. Hypersexual
  4. Hyper Aggressive
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15
Q

Imaging Picks?

A

Frontotemporal degeneration

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16
Q

Presentation Lewy body dementia?

A
  1. Parkinsonian symptoms - only a few symptoms
  2. Dementia - predominates
  3. Visual hallucinations
17
Q

MRI with loss of substantia nigra and dementia?

A

Picks disease

18
Q

Presentation Vascular dementia?

A
  1. Stepwise decline with each stroke with each stroke

2. Alzheimer

19
Q

Difference in vascular dementia and alzheimer’s?

A
  • Alzheimer’s is a gradual decline

- Vascular is a step down with each stroke

20
Q

Pathology CJD?

A

Prions / undercooked meat / mad cow

- Most often from a sporadic mutation

21
Q

Presentation CJD?

A
  1. Extremely young dementia

2. MYOCLONUS

22
Q

Diagnosis CJD?

A

MRI

23
Q

Prognosis CJD?

A

Usually die in six months

24
Q

Pathology NPH?

A
  1. Increased ICP
25
Q

Presentation NPH?

A
  1. Wet - urinary incontinence
  2. Wobbly - Ataxia
  3. Weird - Dementia
26
Q

Diagnosis NPH?

A
  1. CT showing hydrocephalus

2. LP with symptoms improving