Olfaction and Taste Flashcards
There are 3 neurons involved in the olfaction pathway.
Neuron 1 is a ______ neuron, neuron 2 has its body in the __________ and it projects directly to olfactory cortices. Neuron 3 has its axon in the ___________.
bipolar, olfactory bulb, uncinate fasciculus
The lamina propria of olfactory mucosa contains ___________ which secrete mucus.
Bowman glands
Olfactory epithelium is __________.
It contains ___________ which provide metabolic and physical support to receptor cells, ________ cells that are proginator cells, and _________ cells which form synapses with CN V fibers and are sensitive to chemical irritants but are not discriminative.
pseudostratified columnar neuroepithelium, sustentacular supporting cells, basal cells (stem cells), microvillar (brush) cells
The basal cell nuclei of the olfactory epithelium is located close to the _________
lamina propria
olfactory receptor neurons are derived from the __________ and have ______ morphology
nasal (olfactory) placode, bipolar morphology
Olfactory receptor neurons are _________ and are covered by ensheathing cells
unmyelinated
Every olfactory receptor neuron has ___ type(s) of receptor for odorants
1
Odorant binding proteins are produced by the ________ cells
sustentacular
The cAMP-activated channels create _______ potentials when an odorant is detected
graded
a single odor can activate ______ odorant receptor(s)
multiple
______ odorant(s) can activate multiple glomeruli and this is referred to as ________
one, cross fiber activation
Cell bodies of periglomerular cells are in the ________ layer
glomerular layer
Tufted cells are found in the ______ layer
external plexiform layer
Mitral cells are found in the ______ layer
mitral cell layer
Granule cells are categorized as _______ and are in the _______ layer
interneurons, granule cell layer
sensory information from olfactory receptor neurons travels through the _______ and enters the ________.
From there it interacts with the ________ cells before being transferred to neurons of the _______ cells and _______ cells. Both of these cell types interact with ________ cells before passing their information onto the _______ tract.
cribiform plate, olfactory glomeruli, periglomerular cells, tufted cells, mitral cells, granule cells, lateral olfactory tract
The main efferent neurons of the olfactory bulb are ______ cells and _______ cells.
tufted cells, mitral cells
Granule cells lack _____
axons
centrifugal fibers provide excitatory input to ________ cells from the _________, ______, and ________.
granule cells, olfactory cortices, locus ceruleus, raphe nuclei
Centrifugal fibers provide feedback inhibition to _______ and _______ cells via __________ synapses
mitral, tufted, GABAergic dendrodendritics
Odorant binding proteins are produced by the ________ cells
sustentacular
The cAMP-activated channels create _______ potentials when an odorant is detected
graded
a single odor can activate ______ odorant receptor(s)
multiple
______ odorant(s) can activate multiple glomeruli and this is referred to as ________
one, cross fiber activation
Cell bodies of periglomerular cells are in the ________ layer
glomerular layer
Tufted cells are found in the ______ layer
external plexiform layer
Mitral cells are found in the ______ layer
mitral cell layer
Granule cells are categorized as _______ and are in the _______ layer
interneurons, granule cell layer
sensory information from olfactory receptor neurons travels through the _______ and enters the ________.
From there it interacts with the ________ cells before being transferred to neurons of the _______ cells and _______ cells. Both of these cell types interact with ________ cells before passing their information onto the _______ tract.
cribiform plate, olfactory glomeruli, periglomerular cells, tufted cells, mitral cells, granule cells, lateral olfactory tract
Granule cells lack _____
axons
centrifugal fibers provide excitatory input to ________ cells from the _________, ______, and ________.
granule cells, olfactory cortices, locus ceruleus, raphe nuclei
Centrifugal fibers send excitatory signals to ________ cells which provide feedback inhibition to _______ and _______ cells via __________ synapses
Granule cells, mitral, tufted, GABAergic dendrodendritic