OESOPHOGEAL CASE STUDY Flashcards

1
Q

What are the two types of oesophageal cancer?

A

adenocarcinoma
squamous carcinoma

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2
Q

How does oesophageal adenocarcinoma form?

A

in the glandular cells which make mucus, due to exposure to stomach acid

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3
Q

What are the symptoms of oesophageal cancer?

A
  • trouble swallowing
  • reflux (GERD)
  • mucus and blood
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4
Q

What is stage 3 adenocarcinoma?

A

cancer that has spread from the oesophagus to lymph nodes and nearby tissues and adventita

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5
Q

What is the prognosis of stage 3 adenocarcinoma?

A

If chemo and radiation is successful, there is a 3-5 year survival rate of 20-30%

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6
Q

What are the treatment options following the biomarkers?

A

HER2POS - HER2 therapy, trastuzumab
PD-L1 neg - immunotherapy invalid

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7
Q

How does chemo work in adenocarcinoma?

A

destroys the cancer cells so they cannot grow or reproduce

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8
Q

How does radiation work in adenocarcinoma?

A

reduces tumour size before surgery

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