Oesophago-gastric Cancer Flashcards
What are the two types of oesophageal cancer?
adenocarcinoma
squamous cell carcinom
What are the three types of gastric cancer?
- Adenocarcinome
- Lymphoma
- GISTs
What causes adenocarcinomas in oesophageal cancer?
Reflux disease - Barrett’s
What causes squamous cell oesophageal carcinoma?
Smoking and alcohol
What is the main cause of gastric adenocarcinomas?
H. pylori
What are two paraneoplastic syndromes of oesophageal cancer?
- hypercalcaemia
2. Inappropriate hormone production
What are dysphagia, odynophagia, haematemesis, regurgitation, dysphonia and weight loss all symptoms of?
Oesophageal cancer
What is abdnominal pain, emesis, anorexia, dysphagia, early satiety and upper GI haemorrhage all symptoms of?
Gastric cancer
What is used to investigation oesophageal cancer and gastric cancer?
Upper GI endoscopy and biopsy
What three imaging studies can be sued for oesophageal cancer?
- Barium meal
- CT (MRI) scan of chest and abdomen
- Bronchoscopy
What are these alarm features of: >55 years of age, dysphagia, evidence of GI blood loss, persistent vomiting, unexplained weight loss, upper abdominal mass and anaemia?
Gastric cancer
What is the only way to cure oesophageal cancer?
Surgery
What two stages of oesophageal cancer cannot have surgery?
T4 and M1
What are 3 contraindications to oesophageal cancer surgery?
- Direct invasion of adjacent structures
- Fixed cervical lymph nodes
- Widespread metastases
What are three other forms of oesophageal cancer treatment other than surgery?
- Radiotherapy
- Intubation/stents
- Canalisation: dilatation, laser, diathermy, alcohol, PDT