GORD and Dysmotility Flashcards

1
Q

What does an incompetent lower oesophageal sphincter, poor oesophageal clearance nad barrier function/visceral sensitivity cause?

A

GORD

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2
Q

What are heartburn. acid reflux, waterbrash, dysphagia and odynophagia symptoms of?

A

GORD

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3
Q

What are 4 investigations for GORD?

A
  1. Endoscopy
  2. Barium swallow
  3. Oesophageal manometry and pH studues
  4. Nuclear studies
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4
Q

What two carcinomas can result from GORD?

A

Oesophageal carcinoma

Oesophageal adenocarcinoma

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5
Q

What are the two pathogenetic steps between a normal oesophagus and an adenocarcinoma?

A

Oesophagitis and Barrett’s

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6
Q

What is the main type of drugs used for GORD?

A

Antacids

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7
Q

What is the one class of drugs to treat GORD - begins with H?

A

H2 antagonists

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8
Q

Name two H2 antagonists?

A
  1. Cimetidine

2. Ranitidine

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9
Q

Name two PPI?

A

Omeprazole

Lansoprazole

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10
Q

What is the name of the surgery for severe/unresponsive GORD?

A

Nissen fundoplication

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11
Q

What is an irreversible result of GORD, occurs in 10% of GORD patients and involves intestinal metaplasia?

A

Barrett’s oesophagus

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12
Q

What are 4 methods of dysplasia management?

A
  1. Optimise PPI dose
  2. Endoscopic mucosal resection
  3. Radiofrequency ablation (HALO)
  4. Argon
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13
Q

What are two types of hiatus hernia?

A

Sliding hiatus hernia

Paraoesophageal hiatus hernia

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14
Q

What is gastroparesis?

A

Delayed gastric emptying

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15
Q

What is one clinical symptom of gastroparesis?

A

Feeling of fullness

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16
Q

What are 4 causes of gastroparesis?

A
  1. Diabetes mellitus
  2. Cannabis
  3. Medication (opiates, anticholinergics)
  4. Systemic sclerosis
17
Q

What investigation is done for gastroparesis?

A

Gastric emptying studies

18
Q

What are these management options form: removal of precipitating factors, liquid/sloppy diet, eat little and often, promotility agents and gastric pacemaker?

A

Management of gastroparesis