Oesophageal cancer Flashcards
1
Q
What are the two types of oesophageal cancer?
A
- Squamous cell cancer
2. Adenocarcinoma
2
Q
Which is the most common type worldwide?
A
Squamous cell cancer
3
Q
Where does squamous cell oesophageal cancer present in the oesophagus?
A
Middle 1/3 of the oesophagus
4
Q
Where does adenocarcinoma oesophageal cancer present in the oesophagus?
A
Lower 1/3 of oesophagus
5
Q
Risk factor for squamous cell cancer?
A
- Obesity
- Alcohol
- Smoking
- Achalasia
6
Q
Risk factor for adrenocarcinoma oesophageal cancer?
A
Barret’s oesophagus
7
Q
Describe the pathogenesis of ‘Barret’s oesophagus’
A
metaplasia of the normal squamous epithelium in the distal oesophagus to columnar epithelium
- squamous –> columnar ( premalignant change)
- increased chance of dysplastic change to adenocarcinoma
