odontogenesis- part 1 Flashcards
what is the budding epithelium known as?
primary epithelial band
when mesenchyme migrate to the maxilla/mandible for tooth formation what signal is released from the epithelium?
FGF8
what does FGF8 cause the mesenchyme to do?
undergo condensation and cluster under the primary epithelial band
what week is primary epithelial band formed?
week 6
what happens in week 7?
the primary epithelial band forms the DL and VL which grow
what happens in week 8?
continued growth of DL and VL
what happens within week 9?
apoptosis of VL begins- in order to form the vestibule
what is the vestibule ?
it is the gap between the soft tissues and the teeth
what happens in week 10-11?
continued growth of DL and continued apoptosis of VL
what happens in week 12?
vestibule is formed creating the sulcus between tooth and labial/buccal surface
what are the 3 stages of tooth development?
initiation
morphogenesis (shaping)
histogenesis
what does the epithelia (ectoderm) form?
enamel and hyaline of the root
what does the ectomesenchymal cells form?
dentine
pulp
cementum
pdl
bone
what happens in the initiation stage of tooth development and what week does this occur?
the epithelial thickens around week 6
describe the bud stage of tooth development and what week it starts?
week 8
-epithelium proliferate and move into mesenchyme- enamel organ formed
-fgfs and baps released from epithelium than cause condensation of ectomesenchyme at bud
-condensed mesenchyme=dental papilla
lots of proliferation at this stage
