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craniofacial development > development of the face > Flashcards

development of the face Flashcards

1
Q

what is the primary ossification centre of the maxilla?

A

infraorbital nerve

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2
Q

when are nasal pits formed?

A

4th week

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3
Q

when are lateral and medial nasal prominences formed?

A

5th week

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4
Q

when does medial nasal prominences fuse and when do they fuse with maxilla to form inter maxillary ligament?

A

week 6/7

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5
Q

what does the frontal nasal form?

A

fore head
bridge of nose

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6
Q

what does the medial nasal form?

A

philtrum and tip of nose

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7
Q

what does lateral nasal form?

A

alae of nose

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8
Q

what does maxillary form?

A

checks and lateral of upper lip

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9
Q

what is the major signalling molecule for the maxilla?

A

retinoic

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10
Q

is cartilage vascular or avascular?

A

avascular

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11
Q

what forms out layer cartilage and what name is given to outer layer?

A

chondroblasts and perichondrium

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12
Q

when chondroblasts are trapped as chondrocytes what are they found within?

A

lacunae

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13
Q

what week does meckels cartilage form?

A

week 6

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14
Q

where does bone lay in comparison to mockers cartilage?

A

alongside the cartilage- it is used as a template

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15
Q

what does the posterior part of meckels cartilage become?

A

malleus (ear) and spehenomalleor ligament

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16
Q

what does 2nd posterior part of meckels cartilage become?

A

disappears but capsule forms sphenomandibular cartilage

17
Q

what does 3rd area of meckels cartilage become?

A

absorbed

18
Q

what does anterior part of meckels cartilage become?

A

undergoes endochondral ossification

19
Q

what kind of cartilage is primary cartilage?

A

hyaline

20
Q

what is CCN2?

A

a growth factor that allows growth and development of mesenchymal tissues of the face

21
Q

what is the 1st stage of CCN2 expression?

A

forms meckels cartilage

22
Q

what is the 2nd stage of CCN2 expression?

A

released from MC and acts as a messanger molecule between chondrocytes and osteoblasts to form bone at surface

23
Q

where does primary ossification occur in the mandible?

A

in-between mental and inscisive nerve

24
Q

where does intraosseous formation occur first?

A

anteriorly and posteriorly up to where mandibular nerve splits into lingual and IAN. and then extends up to form ramus of mandible

25
Q

when does primary ossification end?

A

10 weeks

26
Q

what forms secondary cartilage?

A

endochrondral ossification

27
Q

what type of cartilage is secondary cartilage?

A

fibrous

28
Q

what are the areas of secondary cartilage of the mandible?

A

coronoid
condyle
symphyseal at chin

29
Q

what is the last secondary cartilage to ossify?

A

condyle- 20 years

craniofacial development (9 decks)

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