Occupational lung diseases Flashcards

1
Q

What is the hierarchy of controls when it comes to management of risk in occupational settings?

A

Start at top and work down:

elimination
substitution
engineering controls
administrative controls
personal protective equipment

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2
Q

List some occupational lung diseases

A

occupational asthma
asbestos related disease
pneumoconiosis
byssinosis
beryllium disease
lung cancers
hypersensitivity pneumonitis
infections
COPD

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3
Q

Trades/industries susceptible to occupational lung disease

A

construction
engineering
welding
foundries/quarries/potteries
motor vehicle repair
stonemasons
farmers

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4
Q

How does asbestos affect the lungs?

A

pleural plaques
diffuse pleural thickening
malignant mesothelioma
asbestosis (example of pneumoconiosis)
lung cancer
laryngeal cancer

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5
Q

When do symptoms of asbestosis usually start?

A

2+ decades following asbestos exposure

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6
Q

Clinical features of asbestosis

A

dyspnoea
non-productive cough
weight loss
fine inspiratory crackles
finger clubbing

smoking increases susceptibility and deterioration

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7
Q

What investigations should be done for suspected asbestosis?

A

spirometry - usually restrictive
reduced transfer factor
CXR - fine nodular shadowing
HRCT - more sensitive than CXR at showing fibrosis
lung biopsy - interstitial fibrosis + asbestos bodies

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8
Q

Asbestosis management

A

supportive
stop smoking
risk of lung cancer increased

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9
Q

What is malignant mesothelioma?

A

cancer affecting the pleura and peritoneum
almost always fatal (usually within 12 months)
strong association with asbestos exposure
long latency period

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10
Q

Malignant mesothelioma presentation?

A

> 20 years after asbestos exposure
chest pain
SOB
pleural effusion (repeated)

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11
Q

Industries at risk of malignant mesothelioma?

A

plumbers/electricians/maintenance
demolition
construction
plumbing + pipe lagging
brake lining manufacture/mechanics
railway engineering
asbestos mining

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12
Q

Which diseases enable an individual to claim Industrial Injuries Disablement Benefit?

A

Asbestosis
Mesothelioma
Primary carcinoma lung
Diffuse pleural thickening
Not pleural plaques

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13
Q

What is work aggravated asthma?

A

provoked symptoms of pre-existing asthma
acute transient airway narrowing after exposure to respiratory irritants eg. dust, smoke, SO2, cold, exercise

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14
Q

What is irritant induced occupational asthma?

A

Caused by:

single exposure to high level or irritant substance eg. ammonia, chloride, hydrofluoric acid

multiple high level exposures

chronic moderate level exposures

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15
Q

What is sensitiser induced occupational asthma?

A

asthma caused by immunological sensitisation to agents in the workplace

latency between weeks and years

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16
Q

What does RIDDOR stand for?

A

Reporting of Injuries, Diseases and Dangerous Occurrences Regulations)

17
Q

How does occupational asthma present?

A

wheeze
dyspnoea
chest tightness
at work or after work, improving over weekends/holidays

18
Q

Causative agents and occupations at risk of occupational asthma?

A

Isocyanates - paint spraying
Cleaning agents - cleaners
Flour - bakers
Animals - Lab workers
Rosin flux fume - electronics
Latex - healthcare
Wood dust - carpentry
Enzymes - detergent manufacture
Persulfate salts - hairdressers

19
Q

How is occupational asthma diagnosed?

A

history - occupation
serial peak flow - looking for >20% variation across shift and lower/more variable peak flow on work days
RAST (specific IgE), skin prick testing
specific inhalation challengw
workplace challenge

20
Q

Occupational asthma treatment

A

BTS guidelines for asthma
often resolves if exposure eliminated

21
Q

What are pneumoconioses?

A

group of diseases caused by inhalation of mineral dust
deposition of dust in alveoli
localised inflammatory response causes longer term changes

22
Q

List the pneumoconioses and their causative agents

A

coal workers pneumoconiosis - coal dust
asbestosis - asbestos
silicosis - silica
slate workers pneumoconiosis - slate
kaolin - china clay
stannosis - tin ore
siderosis - iron oxide

23
Q

Occupational causes of lung cancer

A

passive smoking
mineral dusts
asbestos
arsenic
nickel