Obstetrics Flashcards
Fundal height formula
umbilicus-20wks+2-3cm/week
Fetal heart via doppler, quickening
Fetal heart: 10-12wk
Quickening: 17-18wks
Quad screen for Trisomy 18, 21 (MSAFP, Estriol, Inhibin A, BHCG)
Trisomy 18: all low
Trisomy 21: MSAFP/Estriol low; inhibin A, Bhcg high
Causes fetal renal tubular dysplasia, neonatal renal failure, oligohydramnios, IUGR, lack cranial ossification in fetus
ACEi
Causes neural tube defects, fingernail hypoplasia, microcephaly, developmental delay, IUGR in fetus
Carbamazepine
Causes bowel atresia, malformation heart, limbs, face, GU; microcephaly, IUGR, cerebral infarct in fetus
cocaine
Causes ebstein anomaly in fetus
Li
Causes cerebral atrophy, microcephaly, mental retardation, spasticity, seizures, blindness in fetus
Mercury
Causes IUGR, mental retardation, microcephaly, dysmorphic craniofacial, cardiac defects, fingernail hypoplasia in fetus
Phenytoin
Causes hearing loss, CNVIII damage in fetus
streptomycin, kanamycin
Causes cleft lip or palate, cardiac defects, microcephaly, mental retardation in fetus
Trimethadione
Causes neural tube defects, minor craniofacial defects in fetus
valproic acid
Causes nasal hypoplasia, stippled bone epiphyses, delayed delay, IUGR
warfarin
causes inc SAB, microtia, thymic agenesis, CV defects, craniofacial dysmorphism, cleft lip, cleft palate, mental retardation in fetus
Vit A
Causes hydrocephalus, intracranial calcifications, chorioretinitis, ring-enhanced lesion on MRI in fetus: dx and tx
Toxo
Tx with pyramethamine and sulfadiazine
spiramycin ppx in 3rd trimester