Obstetrics Flashcards
How does the airway change in the parturient?
Increased mallampati score
Diff intubation is 8x higher
Glottic opening is narrowed (smaller tube)
Datta handle (shorter) is useful
Tissue in nasapharynx is friable
Increased airway edema
What hormone relaxes the ligaments in the rib cage?
Relaxin
How is the lung affected in the parturient?
Decreased FRC
Increased O2 consumption ~ onset of hypoxemia is quick
Airway closure during tidal breathing.
Which hormone is a resp stimulant?
Progesterone
What is the ABG for a parturient?
pH ~ normal
PaCO2 ~ decreased (30ish)
PaO2 ~ ^ 105ish
HCO3 ~ decreased (20ish)
How does the OxyHgb dissociation curve shift?
Increase in P50 > shift to the right
***facilitates transfer of O2 to fetus
How does minute vent change in the parturient?
Increase in tidal volume
Increase in resp rate
**overall increase in minute ventilation
How do lung capacities change in the parturient?
TLC ~ decreased
VC ~ no change
FRC ~deceased
Expiratory reserve ~ decreased
Residual volume ~ decreased
Closing capacity ~ no change
How does the oxygen consumption change for the parturient?
Term: 20%
First stage of labor: 40%
Second stage of labor: 75%
How does O2 consumption change for the parturient?
Increases 20%
How does cardiac output change for the parturient?
Increased by 40%
HR ~ ^
SV ~ ^
***CO during labor is different
1st stage: 20%
2nd stage: 50%
3 stage: 80% (auto transfusion from placenta)
How does BP change for the parturient?
MAP ~ no change
SBP ~ no change
DBP ~ decreased
Increased in volume + decrease in SVR = net effect
How does vascular resistance change in the parturient?
Decreased SVR and PVR
***progesterone increases nitric oxide
(They have a decreased response to angiotensin and NE!!)
How do filling pressure change for the parturient?
No change due to compensatory vascular changes
How does the cardiac axis change in the parturient?
Left deviation
At what point should we displace the parturient mother’s right torso to relieve aortocaval compression?
2nd or 3rd trimester
How does the intravascular fluid change for the parturient?
Increased by 35%
- increased plasma
- increase RBCs
**this prepares mom for hemorrhage with labor
How does the hematological system change for the parturient?
Pregnancy causes HYPER-COAGULABLE state
Clotting factors: increased (1, 7, 8, 9, 10, 12)
Decreased antithrombin
Decreased protein S
Increased fibrin breakdown
Decreased 11 and 13
What is the bottom line for the parturient and her hematological state?
Mom makes more clot, BUT she also breaks it down faster
what are the neurological changes with pregnancy?
Decreased MAC
Increased sensitivity to local anesthetics ~ decreased epidural space and increased epidural vein volume
What are the GI changes in the parturient?
Increased gastric volume
Decreased gastric pH
Decreased sphincter tone
Decreased gastric emptying (after labor begins)
How is the renal system affected in the parturient?
Increased GFR (blood volume)
Increased creatinine clearance (blood volume)
Increased glucose in urine (d/t increased GFR)
**decreased creatinine and BUN (d/t increased creatinine clearance) obvs!!
What is uterine blood flow?
700-900 mL/min
How does preganancy affect serum albumin?
Decreases
How does pregnancy affect pseudocholinesterase?
Decreases (but not meaningful for sux)
Is uterine blood flow autoregulates?
NO!! Dependent on maternal MAP, CO, and uterine vascular resistance
What % of cardiac output is uterine blood flow in the parturient?
10%
What does new research say about neo for pregnant moms?
It’s just as good as ephedrine with LESS fetal acidosis
What type of meds can easily transfer via the placenta?
Local ansthetics
IV anesthetics
Volatile anesthetics
Opioids
Benzos
Atropine
Beta-blockers
Mag
What types of meds can’t transfer the placenta?
NMB
Heparin
Insulin
Glyco
When does the first stage of labor begin/end?
Begins: cervical dilation
Ends: full cervical dilation (10 cm)
**divided into latent and active phase
When does the second stage of labor begin?
Begin: with full cervical dilation
Ends: the delivery of the newborn
**pain in the perineum begins here!
When does the third stage of labor begin/end?
Begin: delivery of the newborn
End: delivery of the placenta
What do the cervical dilation in the latent phase?
Latent phase ends when cervix is 2-3 cm dilated
What is the cervical dilation in the active phase?
Active phase occurs when cervix is 3-10 cm dilated
When is a laboring mom considered a full stomach?
Always!!!
When can a laboring mother who is healthy drink?
Moderate amount of clear liquids throughout labor
When can a laboring mother who is healthy eat food?
Up until a neuraxial block is placed
Does an epidural prolong first stage of labor?
NO!
Does an epidural increase the need for a c-section?
NO!
Where is the pain located in the first stage of labor?
T10-L1
Lower uterine segment and the cervix
Where is the pain located during the second stage of labor?
S2-S4
In addition of pain from vagina, perineum, and pelvic floor
Neuraxial techniques must be extended to cover S2-S4 range
What are appropriate regional techniques for the first stage of labor? I.e. T10-L1
Epidural
Paravertebral lumbar block
Paracervical block (high risk of fetal bradycardia)
What are appropriate anesthetic techniques for the second stage of labor? S2-S4
Neuraxial or Pudendal nerve block
What are some consequences of uncontrolled pain?
Increased maternal catecholamines > hypertension and reduced uterine blood flow
Maternal hyperventilation > alkalosis > leftward shift > decreased delivery of O2 to the fetus
What is the most common CSE approach?
“Needle through the needle”
What is the epidural volume extension technique?
Injection of saline into the epidural space immediately after the local anesthetic is administered into the subarachnoid space
*compresses subarachnoid space ~ enhances rostral spread
Does Nitrous 50/50 (50% O2) affect uterine contractility?
It doesn’t!
Which local anesthetic reduces the efficacies of epidural morphine?
2-Chloroprocaine ~ antagonizes Mu and kappa receptors
What is a pure S-enantiomer of Bupivacaine?
Levobupivacaine
Less CV toxicity (not available in US though) :(
Which local anesthetic is useful in emergency c/s when epidural is ALREADY in place?
2-Chloroprocaine
Min. Placental transfer
Why is lidocaine not popular for labor analgesia?
Very strong motor block, BUT it’s great for C/S
Which enantiomer of Bupivacaine is associated with cardio toxicity?
R-enantiomer.
0.75% contraindicated via epidural due to risk of toxicity!