Obstetrics Flashcards
what is perinatal?
pregnancy + 1 year post partum
what is the difference between baby blues, PND and psychosis in terms of time frame?
- baby blues: <2 weeks
- PND: 2-4 weeks
- Psychosis: recover within 6-12 weeks
what extra features need to be in the antenatal care in patients with cardiac disease in pregnancy?
- echo at booking and at 28 weeks
- anticoagulant if patient has: CHD, pulmonary HTN, artificial valves
- prophylactic Abx for women with structural heart defects
what extra scans should happen in pregnant women with diabetes?
28, 32, 36 (4 weekly serial growth scans)
cardiac outflow scan
retinal and renal scanning
what other appointments should pregnant women have?
every 2 weeks = joint antenatal-diabetes clinics
when should pregnant women with diabetes deliver?
37+0 to 38+6 weeks = induction or ELCS
what signs can be seen on USS in ectopic pregnancy?
- Tubal: bagel/blob sign
- Cervical: barrel cervix
what extra medication should be recommended for pregnant women with epilepsy?
- Vit K in last month of pregnancy
- increased folate dose
- epidural for delivery
what can you recommend to pregnant women with Epilsepy?
UK Epilepsy and Pregnancy register
appearance of complete and incomplete mole on USS
- complete mole: snowstorm/”cluster of grapes”
- incomplete mole: foetal parts
what is the management of a molar pregnancy?
URGENT referral to specialist centre
1. surgical: ERPC
2. monitor bHCG - methotrexate if rising/stagnant
AVOID pregnancy until 6 months of normal levels
what is the main issue with GTD malignancy?
rapid metastasis
3 main types of GTD malignancy
- invasive mole
- choriocarcinoma
- placental site trophoblastic tumour
what is an invasive mole?
- hydatiform mole
- invasion of myometrium
- necrosis
- haemorrhage
what is a choriocarcinoma?
cytotrophoblast and syncytiotrophoblast without formed chorionic villi invade myometrium
what is placental site trophoblastic tumour?
intermediate trophoblasts infiltrate myometrium without causing destruction
what PUQE-24 score indicated admission?
13+
when else might you admit in HG?
- if can’t keep fluids down
- ketonuria
- weight loss >5%
- co-morbidities
what medication do you give HG?
- VTE
- KCl
- Thiamine
what is classified as HTN in pregnancy? what target do you try and achieve?
> 140/90
target: <135/85
what do you give for high risk pre-eclampsia?
aspirin 75mg from 12 weeks to birth
what are the high risk factors for pre-eclampsia? how many do you need to give aspirin?
1+ = aspirin
- previous pre-eclampsia
- CKD
- AI disease
- T1 or T2DM
- Chronic HTN
what are the low risk factors for pre-eclampsia? how many do you need to give aspirin?
2+ = aspirin
- Primigravid
- age 40+
- pregnancy interval >10 years
- BMI >35
- FHx pre-eclampsia
- multiple pregnancy
what is the definition of moderate HTN?
140/90 to 159/109
what checks do you need to do for moderate HTN?
- BP: measure 1-2/week
- Dipstick: 1-2/week
- FBC, LFTs, U&Es: ONCE at presentation
- USS for foetal growth
what is the definition of severe gestational HTN?
> 160/110
what checks do you need to do in severe gestational HTN?
- BP: measure every 15-30 mins until <160/110
- Dipstick: daily whilst admitted
- FBC, LFTs, U&Es: ONCE at presentation
- USS for foetal growth
after discharge, what do you then do for moderate and severe gestational HTN?
- measure FBC, LFTs, U&Es ONCE a week
- every 2-4 weeks: USS for foetal growth, umbilical artery doppler, amniotic fluid assessment, dipstick, BP measurement
if the patient has chronic HTN, when do you do assessments?
assess at 28, 32, 36 weeks only
what checks do you do in moderate pre-eclampsia (140/90)?
- BP: inpt = x4/day, outpt = every 48 hours
- blood: x2/week
- Admission: CTG, USS, umbilical artery doppler, amniotic fluid assessment
what checks do you do in severe pre-eclampsia?
- BP: every 15-30 minutes until <160/110, then x4/day as inpt
- Bloods: x3/week
- Admission tests: same as moderate
following discharge or going forward what checks need to be done in moderate and severe pre-eclampsia?
- every 2 weeks: USS, umbilical artery doppler, dipstick, BP measure
- moderate: bloods x2/week
- severe: bloods x3/week
- > 37 weeks = initiate birth 24-48hrs
what is the pre-eclampsia postnatal discharge criteria?
- no symptoms
- BP < 150/100
- blood tests stable or improving
what is the inpt and outpt postnatal BP monitoring?
- inpt: x4/day
- outpt: every other day until targets achieved, then once weekly
what is the pre-eclampsia aetiology?
impaired trophoblastic invasion of spiral arteries
- impaired invasion = high resistance flow
- low flow = poor perfusion of placenta
- placenta releases factors into circulation
- promotes further systemic effects
what are the symptoms of toxoplasmosis in the mother?
asymptomatic
fever, malaise, arthralgia
treatment of mother with toxoplasmosis
Spiramycin
symptoms of congenital toxoplasmosis
- chorioretinitis = cataracts
- hydrocephalus
- convulsions
- intracranial calcifications
investigations for toxoplasmosis
Sabin Feldmen Dye Test
management of congenital toxoplasmosis?
pyrimethamine, sulfadiazine
what are the symptoms of congenital syphillis?
- rash (soles and palms)
- bloody rhinitis
- nose deformity
- saber shin’s (anterior bowing of shins)
- Hutchinson’s teeth (small widely spaces, notched)
- Clutton’s joints (symmetrical knee swelling)
investigations of congenital syphillis
- micro
- serology (non-treponemal or treponemal)
management of syphillis
Ben-Pen
+ prednisolone in mum
what are all the different names for parvovirus infection?
- erythema infectiosum
- fifth disease
- slapped cheek
when is transmission highest in parvovirus infection?
higher transmission <20 weeks
what investigations do you do in parvovirus and when are they indicated?
only if contracted if <20 weeks
Foetal anomaly scan USS after 4 weeks, serial scans then every 2 weeks until 30/40
management of in utero parvovirus
in utero transfusions
what are the potential complications of maternal VZV infections?
risk of encephalitis, pneumonia and sepsis
management of a mother exposed/ infected with VZV?
- exposed <20/40 = VZIG (if no symptoms)
- symptomatic and >20/40 = aciclovir
- referral to foetal medicine specialist at 16-20 weeks or 5 weeks after infection
what are the symptoms of congenital varicella syndrome?
- eyes (chorioretinitis)
- CNS (microcephaly)
- MSK (cutaneous scarring, limb hypoplasia)
- IUGR
what are the symptoms of neonatal varicella infection?
- mild disease
- disseminated skin lesions
- pneumonia
- visceral infections (e.g. hepatitis)
management of neonatal varicella infection
aciclovir
arrange neonatal opthalmic exam
what are the indications for neonatal VZIG?
- birth <7 days of mum rash
- mum chickenpox <7 days since delivery
how do you test neonates for HIV?
- neonates test +ve for HIV Abs due to passive transfer
- instead do direct viral amplification through PCR at birth, discharge, 6w, 12w, 18w
what maternal HIV monitoring should be carried out?
- 2x CD4 counts (baseline and delivery)
- x8 viral load (every 2-4 weeks, 36 weeks and after delivery)
symptoms of rubella
- coryzal symptoms, arthralgia, rash
- maculopapular rash
- soft palate lesions
- lympadenopathy
management of rubella in pregnancy
supportive
offer TOP <16 weeks
refer to foetal medicine unit and HPT
when is the biggest risk of congenital rubella syndrome?
<12 weeks of GA
what are the symptoms of congenital rubella syndrome?
- chorioretinitis
- PDA
- SNHL
- microcephaly
what is the most common congenital infection?
CMV
symptoms of CMV in the mum
asymptomatic
what is CMV likely to be vertically transmitted?
30-40% vertical transmission at ANY STAGE
how many pt are asymptomatic for congenital CMV at birth?
90%
what are the symptoms of congenital CMV?
- SNHL
- chorioretinitis
- periventricular calcifications
- blueberry muffin rash
- jaundice
management of congenital CMV
- ganciclovir and valganciclovir
- audiology and ophthalmology F/U
what are the symptoms of HSV in neonate?
- SEM disease (blistering vesicular rash, chorioretinitis)
- CNS +/- SEM (seizures, irritability, lethargy, bulging fontanelle)
- disseminates (encephalitis, CNS, hepatitis, pneumonitis
management of HSV in neonate
aciclovir
when do you treat HSV in mother?
only treat if primary infection
what delivery method if recommended in a mother with primary HSV?
- 1st episode >6 weeks prior to EDD = SVD
- 1st episode <6 weeks prior to EDD = CS
what special precautions should be made in SVD in mothers with HSV?
- avoid invasive procedures
- aciclovir intrapartum
how should mothers with recurrent HSV infection deliver?
- SVD
- aciclovir TDS from 36 weeks
what is the GBS bacteria ?
streptococcus agalactiae
indications for intrapartum GBS prophylaxis?
- intrapartum fever, confirmed chorioaminitis
- prolonged ROM
- <37 weeks (preterm)
- previous infant with GBS
- maternal GBS bacteriuria, colonisation
when should you monitor neonatal vital signs ?
if Abx were given <4 hours before delivery
when is sepsis monitoring needed in newborns?
- 1 RF: hospital Obs 24 hours
- >2 RFs or 1 red flag: sepsis Abx and septic screen
what are the sepsis red flags?
- intrapartum Abx for sepsis (not GBS prophylaxis)
- respiratory distress >4 hours postpartum
- seizures
- mechanical ventilation needed in term baby
- signs of shock
what is classed as engagement?
2/5th palpable or below
what is the 1st stage of labour?
Painful uterine contractions –> 10cm dilation
- Latent = painful contractions to 4cm
- Established = regular contractions, >4cm
what is the second stage of labour?
urge to push to delivery of the foetus
- passive (not pushing)
- active (pushing)
what is the 3rd stage if labour?
delivery of placenta and foetal membrane
where is the pelvic inlet/outlet widest?
- pelvic inlet widest = TRANSVERSE
- pelvic outlet widest = AP
what controls the progression of labour?
power
passage
passenger
what is restitution?
bringing head in line with shoulders
what are the steps to labour?
- head floating, before engagement
- engagement, flexion, descent
- further descent, internal rotation
- complete rotation, beginning extension
- complete extension
- restitution (external rotation)
- delivery of anterior shoulder
- delivery of posterior shoulder
what are the signs and symptoms of shoulder dystocia?
- difficult face/chin delivery
- “turtling”
- failure of restitution
- failure of shoulder descent
shoulder dystocia manoeuvres?
- Rubin’s: push anterior shoulder towards baby’s chest
- Wood Screw’s: Rubin + push posterior shoulder towards baby back
- deliver posterior arm
what is included Bishop’s score?
- cervical position
- cervical consistency
- cervical effacement
- cervical dilation
- fetal station