Obstetrics 1 Flashcards
What USS measurement is most useful for fetal gestation estimation earlier on in pregnancy (9-14 weeks, so for booking scan)?
Crown rump length
What fetal measurements are used later on in pregnancy, so from 14 weeks onwards?
Head circumference, fetal abdominal circumference
What is parity?
Number of potentially viable births >24 weeks
Parity score?
Para = x + y x = number of births over 24 weeks, stillbirth or normal etc. y = miscarriages, ToPs
What is gravidity?
Number of times been pregnant including current pregnancy
E.g. G6 P3+2
FLIPPERBUS?
Fundus (SFH) LIe and liquor - feel all round Presenting Part Engagement Rate and auscultation BP Urine Swelling
When is the uterus first palpable during pregnancy? When might this be earlier?
12-14 weeks
Earlier in multiple pregnancy
At what gestation is fundus of uterus roughly umbilical level? What implications does this have for SFH?
20 weeks
From that point, SFH roughly correlates to gestation +/- 2cm
Discuss engagement of fetal head?
5/5 palpable = fully above pelvic brim, not engaged
3/5 = generally engaged
How many routine antenatal visits would a nulliparous woman have?
10
How many routine antenatal visits would a multiparous woman have?
7
Normal folic acid supplementation?
400micrograms per day til > 12 weeks
Specific examples of food poisoning that can affect pregnant woman badly?
Listeriosis - milk
Salmonella - chicken, eggs
When should booking visit be done?
10-12 weeks
What is the combined test for Down’s syndrome screening?
Nuchal translucency
PAPPA
BhCG
What infections need to be screened for at booking visit?
BBVs e.g. Hep B, HIV Syphillis Rubella STIs - chlamydia, BV, gonorrhoea Asymptomatic bacteruria
What non-infectious conditions need to be enquired about at booking visit?
Haemaglobinopathies and anaemia
Clotting dysfunctions
Pre existing disease, e.g. Cardiac
Rhesus status
When is the anomaly scan done? What are you looking for?
18-20 weeks
NTDs +/- fetal echocardiography
When is rhesus anti-D routinely given prophylactically during pregnancy?
28 weeks and then 32 weeks
What is assessed at 36 week visit?
USS for fetal presentation - offer ECV if breech
When does early morning sickness often resolve in normal pregnancy?
By end of first trimester, 16-20 weeks
What is Naegele’s rule?
EDD = LMP + 9 months + 7 days
What yeast infection are pregnant women more susceptible to?
Candidiasis (thrush)
5 blood tests associated with Down’s syndrome screening?
BhHCG PAPP Oestriol Inhibin A Alpha FetoProtein
What USS marker is used in Down’s syndrome screening?
Nuchal translucency
What is amniocentesis and when is the earliest it should be done?
US guided removal of amniotic fluid
Earliest 15 weeks
What 3 types of disease can amniocentesis be used to investigate?
Chromosomal abnormality
Infection
Inherited disease
Which has a higher miscarriage rate, amniocentesis or CVS?
CVS
What is chorionic villous sampling? Earliest it can be done?
Trophoblast (placental) biopsy
Earliest 11 weeks
What is CVS especially good at detecting?
Chromosomal abnormalities
2 major RFs for Down’s syndrome?
High maternal age
Previously affected baby
What signs of Down’s syndrome may be visible on USS?
Nuchal translucency
Cardiac abnormality (tricuspid regurge)
Short nasal bone
What are the 4 constituents which constitute the combined test for Down’s syndrome?
Maternal age
Nuchal translucency
BhCG
PAPP
What blood markers are raised in Down’s syndrome screening?
BhCG
Inhibin A
What blood markers are reduced in Down’s syndrome screening?
PAPP
Oestriol
Alpha FetoProtein
What is Edwards syndrome?
Trisomy 18
What is trisomy 18?
Edwards syndrome
What is trisomy 13?
Patau’s syndrome
What is patau’s syndrome?
Trisomy 13
What is Klinefelters syndrome?
47 XXY - infertile males
What chromosomal abnormality commonly causes infertility in males?
Klinefelters 47XXY
What is turners syndrome?
45XO - infertile females
What chromosomal abnormality commonly causes infertility in females?
Turners 45XO
What blood marker is raised in NTDs?
Alpha FetoProtein
What congenital abdominal wall defect often occurs in the absence of any other abnormalities?
Gastroschisis
How do congenital GI defects often present antenatally?
Polyhydramnios - impaired swallow
What GI defect is common with Down’s syndrome?
Duodenal atresia
What is fetal hydrops?
Fluid accumulation in 2 or more fetal compartments e.g. Skin oedema and pleural effusion