Emergency And Ward Medicine Flashcards
Important differentials for acute lower abdo pain in any woman of childbearing potential?
GI stuff
Ectopic pregnancy
Ruptured ovarian cyst, ovarian torsion (ovarian accident)
(Miscarriage)
5 step approach to ABGs?
Patients clinical picture
Oxygenation
pH
Respiratory component - CO2 as marker of ventilation
Metabolic component - bicarbonate and base excess
What indicates respiratory involvement on an ABG? How?
CO2 - if it is in the ‘expected direction’ e.g. High in an acidosis then it is a respiratory acidosis, if in the ‘opposite’ direction it is a compensatory change for a metabolic disturbance
Describe the role of base excess in ABGs?
Essentially the CO2 equivalent for metabolic disturbance - if in the ‘expected direction’ of pH change then it is a metabolic disturbance (e.g. Negative = metabolic acidosis)
2 important causes of coma + sweating?
Sepsis
Hypoglycaemia
What does the serum anion gap represent?
The unmeasured anions - albumin, phosphate, sulphate, lactate, ketoacids
KLAPS of unmeasured anions?
Ketoacids Lactate Albumin Phosphate Sulphate
2 causes of a low anion gap?
Lithium toxicity
IgM/IgG multiple myeloma
5 causes of a raised anion gap?
Ketoacids - alcohol or DM
Lactate (sepsis)
Sulphate/phosphate - AKI
Uraemia
Which type of bilirubin is water soluble and therefore detectable directly and visible in urine?
Conjugated
What does bilirubinuria suggest?
Conjugated bilirubin (as this is the only type that is water soluble) - cholestasis
3 causes of isolated raised ALP?
Paget’s disease
Normal pregnancy
Bony mets/blastic lesions e.g. Breast, prostate cancer
2 causes of a low ALP?
Hypothyroidism
Pernicious anaemia
Metabolic cause of a really really low ALP in the context of acute liver failure?
Willsons disease
2 causes of an isolated raised AST?
Rhabdomyolysis
Acute MI
What does a raised ALT and AST with a predominant AST suggest?
Alcoholic disease
5 major causes of a macrocytic anaemia?
Pernicious Other B12/folate def Alcohol Hypothyroidism Reticulocytosis
5 SIRS criteria?
HR > 90
RR > 20
Temp >38.3 or 12000 or
What blood abnormality may be present in non-diabetics in the context of SIRS?
Raised BM