Misc Neuro/Mental Flashcards
What law suggests that memories are lost from most recent to furthest back in dementia?
Ribot’s law
What is astereognosis?
Inability to recognise familiar objects by touch alone
What is tactile agnosia?
Not able to identify stuff drawn on hand
3 areas of frontal lobe function?
Motor
Speech (Brocas)
Prefrontal area - personality, judgment, abstract thought
What is frontal lobe syndrome?
Disinhibition, facetious humour, apathy, distractibility, perseveration, urinary incontinence
2 temporal lobe functions?
Memory (hippocampus)
Speech (Wernickes) - deficit in which results in fluent aphasia
3 parietal lobe things?
Tactile sensation
Visual and auditory sensation
Integration, planning and sequencing
What will a non-dominant parietal lobe lesion yield?
Dressing apraxia Sided neglect of dominant side (usually L) Problems with visuospatial awareness Anasagnosia Autotopagnosia
What does a dominant parietal lobe lesion yield?
Can’t tell L from R
Literacy and numeracy trouble
What is anasagnosia?
Failure to recognise ones own disability, typical of parietal lobe lesions
What is autotopagnosia?
Misidentification of ones own body parts
Non-epileptic tendencies of TLE?
Rf for schizophrenia
Explosive aggressiveness
Reduced libido
What is Pick’s disease?
A cause of Frontotemporal dementia syndrome characterised by early personality and behaviour change with language difficulty (finding words) and late memory change
What histological findings characterise Picks disease?
Tau inclusion bodies conforming to silver stain aggregations
3 defining characteristics of a learning disability?
Intellectual deficit (IQ 70 or less) Social or adaptive dysfunction Onset in developmental period (thus excluding dementia, head injury)
IQ definitions of varying learning disability severity?
Mild = 50-70 Moderate = 35-50 Severe = 20-35 Profound = less than 20
What is fragile X syndrome?
Inherited (X linked) disorder causing learning difficulties, behavioural and concentration problems, hyperactivity and avoidance of eye contact
Physical features of fragile X?
Large head with long prominent ears
Lax joints, mitral valve prolapse, scoliosis, flat feet
What blood parameter doesn’t need to be checked for lithium therapy?
LFTs
4 types of EPSEs?
Acute dystonic reaction
Parkinsonisms
Akathisia
Tardive dyskinesia
Triad of normal pressure hydrocephalus?
Gait disturbance (due to affect on sacral nerves) +/- pyramidal signs
Urinary +/- bowel incontinence for same reason
Slowly progressive, reversible dementia
3 common causes of communicating hydrocephalus?
Infarct of arachnoid granulations
SAH
Meningitis
Signs of hydrocephalus in kids?
Acute signs of raised ICP Chronic FTT, developmental delay Dilated scalp veins and tense fontanelles Hypertonia 'Setting sun' sign on eyes
Chronic signs of adulthood hydrocephalus?
Increasing head size Gait spasticity and unsteadiness Impaired upward gaze (neck pain) 6th nerve palsy Cognitive decline
What is pharmacokinetics?
What the body does to the drug - absorption, distribution, metabolism, excretion