obs and. gynae physio Flashcards

1
Q

what cells produce testosterone

A

Leydig cells

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2
Q

The Y chromosome so males contains what gene

A

SRY

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3
Q

what ducts forms male genitalia

A

Mesonephric (wolffian)

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4
Q

what gender has anti Mullerain hormone that degenerates the paramesonephric ducts

A

males

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5
Q

what ducts allow for the development of female genitals

A

paramesonephric

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6
Q

what leads to a bicornate uterus

A

fusion of the paramesonephric ducts

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7
Q

what cells form the blood testis barrier

A

sertoli cells

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8
Q

when sperm enter the female they undergo what

A

capacitation - removal of cholesterol and glycoproteins from the head of th esperm to allow it to bind to the zonal pellucida of the egg cell

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9
Q

what connective tissue cells can respond to LH and can secrete andorgens under its influence

A

theca folliculi

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10
Q

what cells form the zona pellucida

A

granulosa cells

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11
Q

consider follicles as secondary when

A

they have antrum (fluid filled space)

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12
Q

what stimulates Leydig cells in the testes to produce testosterone

A

Lh

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13
Q

what drives sperm production in sertoli cells

A

FSH

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14
Q

in females LH binds to what cells and that produces androgens

A

theca cells

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15
Q

in females FSH binds to what cells

A

granulosa cells - increase activins and inhibins (have positive and negatvie feedback on the pituitary)

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16
Q

when is the only time oestrogen positively feedback on LH and FSh

A

if there is high oestrogen levels

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17
Q

progesterone is released by what in females

A

corpus luteum

18
Q

what has an inhibitory effect on LH and FSH

A

progesteroen

19
Q

rise in LH causes what

A

increase in progesteron in females and increase in testosterone in males

20
Q

rise in FSH causes what

A

increase in oestrogen synthesis and oogenesis in females and onset of sperm production in males

21
Q

most common condition of hypergonadotrophic hypogonadism in males is

A

Klinefelters

22
Q

body temperature increases in what phase

23
Q

there is a peak of wha tin luteal phase

A

progesterone

24
Q

dysmenorrhoea refers to

A

painful periods

25
menopause characterised by reduction of
circualting oestrogen
26
although oestrogen decreases in menopause what increase significntly
levels of FSH and LH
27
what protects bone mass
oestrogen
28
oestrogen is protective against what
heart disease
29
when is classed as early menopause
between 40-45
30
pre eclampsia is due to failed or incomplete differentiation of what cells
cytotrophoblastic cells
31
umbillical vein and arteroes are opposite ie
umbillical vein delivers oxygenated blood and umbillical arteries are used to transport deoxygenated blood
32
ductus arteriosis bypasses the
lungs
33
ductus venosus bypasses the
liver
34
patent ductus arteriosus has a
continous machinery murmur
35
widely split second heart sounds
patent foramen ovale
36
acrosomal reaction involbes
release of enzymes that digest the zona pellucida
37
38
what is it called when the zona pellucida is digested and the sperm fuses with the cell membrane of the oocyet. this causes icnrease in calcium levels
cortical reaction
39
what is responsble for iniitaing uterine contractions
oxytocin
40
what T3 and T4 levels rise in pregnancy
total
41
what leads to a decrease in blood pressure in the first and second trimester of pregnancy
progesterone