last min gynae Flashcards

1
Q

Inhibin selectively inhibtis

A

FSH

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2
Q

thec cells produce andogens from cholesterol by

A

LH

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3
Q

drop in what causes dom follicle

A

FSH

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4
Q

whats most likely to be the dom follcile

A

high conc of FSH induced LH receptors

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5
Q

inhibin acts to decrease

A

FSH

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6
Q

androgens rise during ovulation - thought to be important in libido

A
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7
Q

LH surge is the best predictor of imminent ovulation and this principle is used in ovulation predictor tests.

A
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8
Q

ovulation occurs when

A

12 hours after the Lh surge

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9
Q

high levels of porgesteron during teh – phase supress LH and FSH

A

luteal

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10
Q

decrease in what causes menstruation

A

progesterone

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11
Q

7 day before period progesterone

A

assesses ovualtion

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12
Q

when is the endometrium in the proliferating vs secretory pahse

A

follicular phse - proliferatin
luteal - secretory

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13
Q
  • is the formation of a specialised glandular epithelium and is an irreversible process and apoptosis occurs if there is no embryo implantation.-
A

decidualisation

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14
Q

menstruation is how long after ovualtion

A

14

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15
Q

mefenamic acid is a

A

prostaglandin inhibitor - act by increasing the ratio of vasconcstrictor to vasodilator ratio

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16
Q

Nsaids such as mefenamic acid is contraindicaed if hsitory of

A

duodenal ulcers or severe asthma

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17
Q

why GnrH analogue bad long temr

A

osteoporosis - however can combine with HRT

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18
Q

GNRH decrease

A

FSH and LH

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19
Q

examples of gnrh analogues

A

buserelin and goserelin

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20
Q

most common reasons for cervical ectropion

A

preg or pill

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21
Q

women with PMB over what age should have 2 week by US for endometrial cancer

A

55

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22
Q

most common cause of post menstual bleedig

A

atrophic vaginits

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23
Q

exception to doing US for if got post mentrual bleeding

A

if on tamoxifen - as they will have a thickened endometrium so need direct visualisation by hysterocscopy and endoemtrial biopsy

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24
Q

first line for endometrial hyperplasia

A

MIRena

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25
LH and FSH in PCOS
LH are very high and FSH are low or normal
26
clomifene works by
blcokign oestrogen negative feedback so more gnrh and more FSH and LH
27
best thing for acne in PCOS
Co-cyrprindol (diannette)
28
dysmenorrhoea
excessive pain during menstrual period
29
primary dysmenorrhoea - usually appears 1-2 years after menarche
secondary dysmenorrhoea- starts many yeats after starting menarceh
30
uterus appears large and globualr
adenomyosis
31
endometrium in muscle layer of uterus
adenomyosis
32
nsaids such as mefenamic acid and ibuprofen are first line for
dysmenorrohoea
33
absent uterus
mullerian agenesis
34
mx for kallamn
HRT
35
ashermann syndrome
secondary to endometrial infection or durgery - secondary amenorrheoa
36
climateric is
time around the beginning of the menopause
37
mx can be avoid what in start of menopause
spicy foods
38
main medical mamagement for troublesome menopasue symptoms
HRT
39
oestrogen only hrt given if not got
uterus
40
hrt oestogen patches avoisd
first past metabolism
41
when given continous vs cyclical hrt
contunous - menopausal cyclical - perimenopsual who still get pridso
42
what decreases risk HRT causing endoemtrial cancer
adding progesterone if got a uteurs
43
Suspected pregnancy Breast cancer Endometrial cancer Active liver disease Uncontrolled hypertension Known VTE Known thrombophilia e.g. factor V leiden otosclerosis
absolute contrainicatiosn to HRT
44
cigarette appearance
lcihen scleorus
45
what is common in lichen sclerosus
splitting of the skin and often leads to superficial dyspareunia
46
mx of lcihen sclerossus
high dose steriods and emollient s-- dermovate (topical steriod)
47
pagets disease is often a sign of
malignancy elsewhere in teh body
48
mucin in epdeirmis in
pagets
49
Benign ovarian cysts are < 5cm in maximum diameter, are physiological and tend to resolve over 2-3 menstrual cycles.
50
what tumour markers recommeded for all pre menopausal woman with compelx ovarian cyst
ca125, afp, beta hcg
51
It is the most common benign ovarian tumour in women <30years
dermoid cysts- as they tend to be big they are more likely to present with torsion
52
if mucinois cysts rupture they can cause
pseudomyxoma peritoneii
53
tender nodualrity on posterior fornixx
endometriosis
54
us shows whirpool sign
ovarian torsion
55
average labour for first time mums is
10hrs and for multi parous women is 5.5
56
1st stage of labour
no more than 12hrs in 1st time mum or 10 in second
57
early latent phase
dilates up to 4cm
58
cord isnt clamped until
pulsations have ceased
59
There are 3 classic signs to indicate separation of the placenta and membranes: The uterus contracts, hardens and rises Umbilical cord lengthens permanently There’s a gush of blood variable in amount Placenta and membranes appears at introitus.
60
increased hyaluronic acid causes cervix to ripen
61
enagment -
passage of widest diamter of the presenting part below the pelvic inlet
62
need to catheterise before using froceps as bladder needs to be empty
63
chignon
swelling on babys head
64
caput succdenaemum
present at brith
65
what haematoma develops several hours after birth
cephalohaemtoma- swelling is firm
66
caput succedaneum
- often occurs due to pressure of the presenting part agaginst the cervix - soft puffy swellign
67
how to induce labour if memebranea are intact
prostaglandin E2 - pessary most commonly used
68
negative nuber if above spine
69
women on anticonvulsants can only take
opiates
70
patietn controleld - pethidine, morphine and remifentatanil (very fast acting and good) -last one
71
ferguson refex - increased uterine contraction due to oxytocin
72
continous electrical fetal monitoring done if
below 37 or after 42
73
A terminal bradycardia is when the baseline fetal hear t rate drops to below 100beats per minute for more than 10minutes. A terminal deceleration is when heart rate drops and does NOT recover for more than 3 minutes.
indicators for emergency c section
74
early decelartion often due to
head compression
75
fetal sleeping - reduced varaibility usually lasts no longer than
40 misn
76
variable deceleration idnciates
cord compression=Cord compression which initially compresses the umbilical vein causing acceleration which is a healthy response. The occlusion of the umbilical artery results in a rapid deceleration. When pressure on the cord is reduced, another acceleration occurs and baseline rate returns.
77
mx of variable deveeraltions
change position of mother
78
sinusoidal pattern on partogram
urgent c section
79
early deceleration are physiological
80
variable deceleration
change position of mother
81
amnioscope detects
fetal Ph
82
reversible causes of death that can be added to the list in preg
eclampsia and intracranial haemorrhaeg
83
most common cause of maternal cllapse - ahemorrhage
most common cause of direct maternal death - thromboemmbolism
84
aortic dissection can have
wide pusle pressure
85
ejection systolic murmurs are common in preg
86
malg sulphate drug toxicity in presence of renal impairemnt
87
in cpr if cardaic output not restored after 3 mins of cpr then do
c secction