OBGYN Crash Course Flashcards

1
Q

How long do pregnancy usually last?

A

37 - 42 weeks since LMP (median 40 weeks)

(around 9 months)

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2
Q

Which weeks are the trimesters divided into?

A
  • 1st: weeks 0 - 13
  • 2nd: weeks 14 - 26
  • 3rd: weeks 27 - 40 (depends on term date)
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3
Q

How do we decide term date? Which rule do we use and what do we do in cases where the rule doesn’t apply?

A

We use Naegele’s rule for 28-day menstrual cycle:

Date of LMP - 3 months + 7 days + 1 year = Term date

OBS! If patient has a menstrual cycle longer or shorter than 28 days, remember to add or substract the difference in days.

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4
Q

Best way of determining term date for sure?

A

USG in the 1st trimester!

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5
Q

How long is the menstrual cycle? Can it vary? And what 2 parts do we divide it into?

A
  • The menstrual cycle is on average 28 days long. But can also vary between being 21 - 35 days long for many.
  • It’s divided into 2 phases called the Follicular phase and the Luteal phase.
  • The Luteal phase alway comes after the follicular phase. No matter how long or short the menstrual cycle is ALWAYS 14 days
  • The follicular phase is on average 14 days, but may vary. In people with 21 day cycle, the follicular phase is for example 7 days (remember, the luteal phase is always 14d)
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6
Q

When does ovulation happen?

A

Ovulation happen is on average the first 24h of the Luteal phase

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7
Q

What kind of significant OBGYN monitoring is epecially used for women in labor?

A

CTG: CardioTokography

Measures 2 things:

  1. Fetal HR (normal 110 - 160)
  2. Contractions (per 10min)
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8
Q

B-hCG: what is normal (no pregancy), what lvl causes a pausitive pregnancy test? When does it peak?

A
  • Negative pregancy test: B-hCG < 5
  • Positive pregancy test: B-hCG > 25 (may already show 8-9 days after ovulation)
  • Peaks between week 8 - 12
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9
Q

Explain the TPAL system

A

System of classifications used in patient history of pregnant women:

  • G (gravidity): number of times patient has been pregnant
  • T(term): number of term pregnancies (>37 weeks)
  • P(parity): number of pre-term pregnancies (between weeks 20 - 37)
  • A (abortions): number spontanous abortions (<20 weeks)
  • L (live births): number of live births in the past
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10
Q

Hematlogic changes due to pregnancy (6)

A
  1. Blood volume increase by upto 50%, mostly being plasma
  2. RBC also increase, but because the plasma increases so much more, we se decreased Hct on blood tests
  3. Hypercoagulative state: increased coagulation factors (5x risk of DVT)
  4. WBC increase, especially plasma cells –> hypergammaglobulinemia (immunglobulin lvl is raised so some can diffuse over to baby and protect it until it can make its own Ig’s), causes also increased ESR
  5. Iron deficiency –> Iron-def anemia (give iron sulfate)
  6. Folate deficiency –> megaloblastic anemia (give folate)
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11
Q

Endocrine changes due to pregnancy? (11)

A

Everything pretty much increases, these are just a few….

  1. High estrogen and progesterone lvls with progesterone being much higher than estrogen
  2. Hyperaldosteronism
  3. Hypercortisolism
  4. Hyperparathyroidism
  5. Hyperthyroidism
  6. Hyperprolactinemia
  7. Increase in Relaxin
  8. Increased Insulin-intolerance –> hyperglycemia
  9. Increased MSH –> hyperpigmentation
  10. Increased HPL
  11. Incresed size of thyroid and pituitary gland
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12
Q

Cardiovascular changes during pregnancy? (6)

A
  1. HR increased by 20bpm
  2. Increased Stroke Volume
  3. Decreased SVR (progesterone is a vasodilator)
  4. Increased pressure in lower veins (uterus press down on IVC)
  5. Ventricualr hypertrophy (changes the PMI)
  6. Midsystolic murmur
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13
Q

Respiratory changes during pregnancy? (3)

A
  1. Decreased RV (cause uterus presses on diaphragm)
  2. Increased TV and Minute-Volume due to increased ligament elasticity from Relaxin release(more movement in ribs and costal ligaments)
  3. Increased RR (causes mild resp-alkalosis, good for the infant as this means more pCO2 can diffuse from placenta to mother)
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14
Q

Renal changes during pregnancy? (8)

A
  1. 100% Kidney-size increase
  2. 50% GFR increase –> low BUN, creatinine, urea
  3. Decreased BUN (makes up for resp alk)
  4. Increased urin glucose (due to hyperglycemia)
  5. Small increase in blood PH within normal values (resp alk)
  6. Incontinence in 3rd trimester (lightening effect)
  7. Proteinuria (though blood albumin lvl is usually increased)
  8. Increased chance of UTI and pyelonephritis due to the high pressures on bladder and kidney causing congestion
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15
Q

Gastric changes due to pregnancy? (4)

A
  1. Decreased gastric motility (constipation) and prolonged emptying time
  2. Decreased LES muscle tone (GERD)
  3. Nausea and Vomiting (can be very severe causing weight loss, Afipran helps nausea and can even increase motility)
  4. Hemorrhoids (remember, uterus presses on IVC)
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16
Q

Dermatological changes during pregnancy (6)

A
  1. Striae gravidarum (strech marks)
  2. Linea Nigra (dark line along the abdomen due to hyperpigmentation)
  3. Chloasma (hyperpigmentation and redness of face and nose)
  4. Spider angiomas
  5. Palmar erythema
  6. Chadwick sign (bluish coloration of vagina and cervix due to cyanosis)
17
Q

What to check during history/physical in first trimester visit? (5)

A
  1. Ask about previous pregnancies and how they went
  2. Take GYN history (menstrual cycle, sex habits etc…)
  3. Chronic and family diseases
  4. Ask about lifestyle (alcohol/drug abuse, teratogenic exposure etc)
  5. Take BMI (determine future weight gain etc)
18
Q

First trimester visit: blood screens to take? (2)

A
  1. CBC, esp to look for iron-def anemia, thallasemia or megaloblastic anemia
  2. Blood typing (Rh- mom’s antibodies attack an RH+ fetus if it’s not the 1st time she’s pregnant)/isoimmunization
19
Q

First trimester visit: infection screenings? (3)

A
  1. Rubella IgG and Varciella IgG (positiv is good, cause it means mother is immune, MMR & Varicella vaccines are not safe during pregnancy)
  2. STD panel: HIV (ELISA + Western) + cervical swab for chlamydia and gonorrhea
  3. HepB screening (even if they have been immunized), if HBsAg positive = give HBIg to baby after birth
20
Q

Why do we we allways obtain urinalysis and culture during the first-trimester visit?

A

To look for Asymptomatic Bacteruria (ASB). This is not harmfull to in non-pregnant individuals, but in pregnant women this can increase chance of pyelonephritis and UTI later in pregnancy, and should be treated with Augmentin immediatly.

21
Q

Which vaccines can NOT be given during pregnancy? (4)

A
  1. MMR
  2. Varicella
  3. Polio
  4. Yellow Fever
22
Q

Which Vaccines CAN be given during pregnancy? (6)

A
  1. Influenza (flu-shot)
  2. Hep A
  3. Hep B
  4. Pneumococcus
  5. Meningococcus
  6. Typhoid
23
Q

What should you check towards the end of first trimester?

A
  1. USG
  2. Serum hCG
  3. AFP (high: twins, very high: neural tube defect)
  4. PAPP-A (low levels suggest aneuploidy)
24
Q

How often are patients followed up during pregnacy?

A

Every four weeks until week 28, then every two weeks until week 36, then every week from then

25
Q

What is the main major complication of the first trimester?

A

Spontanous Abortion!! Usually around week 9